Repositório RCAAP

PONTE , Carlos Roger Sales da . Sobre os conceitos de indivíduo em Sören Kierkegaard e de pessoa em Carl Rogers: semelhanças e diferenças . 2010. 119 f. Dissertação (Mestrado em Psicologia) – Universidade Federal do Ceará, Departamento de Psicologia, Programa de Pós-Graduação em Psicologia, Fortaleza-CE, 2010.

CASTRO, Carolina Aires de. Dando conta da "doença dos nervos": produção de sentidos em conversas com mulheres. 2010. 162f. Dissertação (Mestrado em Psicologia) – Universidade Federal do Ceará, Departamento de Psicologia, Programa de Pós-Graduação em Psicologia, Fortaleza-CE, 2010.

AMORIM, Luciano Jorge. Sistema integrado de rastreabilidade: uma ferramenta para impulsionar o desenvolvimento da cadeia produtiva do camarão cultivado no Estado do Ceará - Brasil. 2008. 89 f. Dissertação (Mestrado em Ciências Marinhas Tropicais) – Instituto de Ciências do Mar, Universidade Federal do Ceará, Fortaleza, 2008.

COSTA, Paulo Sérgio Rocha; SANTOS, Marcelo Antonio Machado dos; ESPÍNOLA, Maria de Fátima Aguiar; MONTEIRO NETO, Cassiano. Biologia e biometria do Coró, pomadasys corvinaeformis (Steindachner) (Teleostei: Pomadasyidae), em Fortaleza, Ceará, Brasil.. Arquivos de Ciências do Mar, Fortaleza. v.29, 1995, p. 20-27

PIMENTEL, Marcionília Fernandes. Análise ecotoxicológica do efluente da indústria de beneficiamento da castanha de caju antes e após tratamento em reator aeróbio inoculado com fungos. 2008. 70f. Dissertação (Mestrado em Ciencias Marinahs Tropicais) - Instituto de Ciencais do Mar, Universidade Federal do Ceará, Fortaleza, 2008.

COSTA, Breno Gustavo Bezerra. Distribuição de Mercurio (Hg) em Sedimento, Água e Biota na Região de Influencia dos Efluentes da Carcinicultura na Gamboa do Cumbe - Rio Jaguaribe - Ceará - Brasil. 2009. 60 f. Dissertação (Mestrado em Ciências Marinhas Tropicais) - Instituto de Ciências do Mar, Universidade Federal do Ceará, Fortaleza, 2009.

BARROSO, Cristiane Xerez. Anatomia e desenvolvimento intracapsular de Neritina zebra (Bruguiere, 1792) (MOLLUSCA, GASTROPODA, NERITIDAE). 2009. 77 f. Dissertação (Mestrado em Ciencias Marinhas Tropicais) - Instituto de Ciências do Mar, Universidade Federal do Ceará, Fortaleza, 2009.

The purpose of this study was to compare the level of apical leakage between canals filled with gutta-percha/AH Plus (GP) and the Resilon/Epiphany System (RES), when submitted to two filling techniques, and to observe, through the use of Optic Microscopy (OM), the adaptation of these materials to the dentinal walls in carried through transversal cuts to 4 mm of the apex. For the evaluation of leakage, seventy extracted human teeth were instrumented and randomly divided into 4 experimental groups in accordance with the material and technique used (lateral condensation and Hybrid technique - HT), and two control groups (positive and negative). After 7 days in an oven (37° C, humidity of 100%), the teeth were immersed in Indian ink and cleared. Leakage was measured by the NIH imageJ program. The exact Fisher test was used to make the comparison between the non-leakage percentages and the non-parametric Mann-Whitney test to measure the leakage when there was any. The value p<0.05 was considered to be statistically significant. With regard to the presence of leakage, there was no difference between the filling techniques (p>0.05), but there was a statistically significant difference when RES was compared with GP (p<0.05), which leaked more than RES. With RES, leakage was confined to the apical third and HT could be used to thermo-plasticize RES with satisfactory results. It was observed through the analysis in OM of 20 remaining teeth, filled in the same way that the experimental groups (5 teeth for each group), that the RES presented many areas mismatch between the material and the dentinal walls, what it would justify occurred leaking with this material.

The replacement of diseased solid organs by healthy ones was one of the greatest advances in medicine in the last century, becoming viable only with the advent of immunosuppressive drugs, which have the ability to inhibit the response of the recipient against the graft. With the development of immunosuppressive drugs and surgical techniques, post-operative risks have become more known, being infection, mainly bacterial, one of the main reasons for the failure of the transplant. Then, microorganisms present in oral infections become a potential threat, even though they are not commonly cited as post-transplant infections promoters on literature. So, it is essential that dentists known the major oral alterations in these patients, and their needs for treatment in order to adopt a conduct to remove oral infections, and eliminating the postoperative risk. The objective of this study was to assess the oral health status and necessity of dental procedures in a group of solid organ transplant candidates. A cross sectional observational study was realized, collecting data from medical records and by an intra-oral exam, realized by a calibrated examiner. A total of 113 patients were examined, being 71 (62.83%) indicated for renal transplantation, 37 (32.74%) for hepatic and 05 (4.43%) for cardiac. The mean age was 42.13 years, and the most prevalent comorbidity was hypertension. The average DMFT index was 17.27 and the most prevalent Community Periodontal Index (CPI) was 02, found in 56 (49.6%) patients, indicating a high prevalence of gingival bleeding on probing and presence of calculus. Most patients in the study (81.32%) showed no soft-tissue lesions. Evaluating the radiographic exams, 56 (49.5%) individuals had horizontal alveolar bone resorption, and 05 (4.43%) patients had partially erupted third molars. Assessing the necessity of dental treatment, periodontal therapy was indicated in 81.5% of patients, 69.9% had restorative indication, 48.6% needed surgical procedures, and 9.7% had indication for endodontic treatment. There was no statistical difference of variables between the three transplant indications. This study concluded that the examined patients had high prevalence of oral diseases, such as caries and gingivitis/periodontitis, and, therefore, a high indication for dental treatment. Careful clinical evaluation should be performed for patients with indication for surgical procedures, minimizing the hemorrhagic risk. Moreover, there is a necessity to focus on oral health promotion within the medical services in patients with different degrees of renal, liver or heart failure, not only during the pre-transplant period, reducing the clinical complications caused by the systemic disease during dental treatment.

Aim: The aim of the present study was to identify the free amino acid content in whole saliva of children with protein-energy malnutrition (PEM), with and without early childhood caries (ECC), correlating these findings with caries experience and mutans streptococci (MS) levels in saliva. Methods: One hundred and twenty two, 12 – 70 months-old children, with or without ECC were selected to participate in the study. Consent forms were signed and children were divided into healthy (GH, n = 47), and mildly (GI,n = 22) or moderately (GII,n = 53) malnourished groups. Malnourishment levels were classified according to WHO 2006 growth standards. Unstimulated whole saliva was collected from all participants and centrifuged. Supernatants were extracted, lyophilized, stored at – 20oC and used for amino acid analysis, on a Biochem 20 plus amino acid analyzer. Stimulated whole saliva was also collected from all subjects, and used for MS detection on MSB agar medium (cfu/mL). Amino acid concentrations were expressed in µM/mL. Dental examination was performed for calculation of dmfs scores. Pearson Chi-Square test and a Logistic Binary Model were used for statistical analysis. Results were considered significant when p-value < 0.02. Results: Forty amino acids were identified, with great variability in their concentrations. Analysis of presence/absence of each amino acid and presence/absence of caries demonstrated an association between asparagine and ECC in GII (p = 0.003). Logistic regression showed that caries experience increased with an increase in age (p = 0.003). The presence of alanine (p = 0.014) and carnithine (p = 0.008) reduced the chances of experiencing ECC. The presence of histidine significantly increased caries risk (p = 0.012). However, MS counts did not significantly increase the risk of experiencing ECC (p = 0.065) in this model. Conclusion: Presence of specific amino acids in saliva of children with PEM predisposes to a higher or lower risk of caries experience.

There is a general consensus that resin-dentin bonds created by contemporary hydrophilic dentin adhesives deteriorate over time. One way to predict how resin-dentin interface would behave over time is aging the specimens in vitro by immersion in different solutions. The objective of this study was to evaluate the effect of immersion in NaOCl solution on the bond interface created by different adhesive systems. For this, it was used 28 human third molars that had superficial dentin exposed and composite build-ups were built on its surface using one of those adhesives, etch-and-rinse: Scothbond Multi-purpose and Single Bond, or self-etch: Clearfil SE and Adper SE. Specimens were cut into nontrimming dentin-composite beams to microtensile testing. After a period of 24 h in distilled water, sticks from each tooth were divided equally into two groups: control or aged in 10% NaOCl for 1 h. Beams were pulled until failure at crosshead speed of 1 mm/min and bond strength was calculated. Fractured sticks were analyzed and classified in: mixed fracture, cohesive in dentin and cohesive in composite; and expressed in percentage. Data from µTBS test were statistically analyzed using Kruskal-Wallis and Games-Howell tests. For comparison between control and aging groups was used the Mann-Whitney test (α=0.05). Two specimens from each adhesive were used to investigate the effect of NaOCl on the interfacial morphological characteristics. For that, specimens were cut in only one direction, dentin-resin discs were fixed in a glass-holder and ground with SiC papers under running water. Slices were treated by Masson’s trichrome acid staining technique to evidence collagen exposed zones and analyzed by optical microscopy. µTBS results showed that NaOCl solution significantly reduced bond strength comparing with the control groups for all adhesives tested. Scothbond MP (control: 39,95±12,72; aged: 26,45±9,90 MPa) showed the highest values and Adper SE (control: 13,21±3,15; aged 4,95±2,49) the lowest in both control and aging groups. Clearfil SE (control : 27,02±6,84; aged: 16,17±3,79) and Single Bond (control : 26,66±8,35; aged: 11,77±4,28) showed no difference in control groups, but after aging, Clearfil SE showed better results. Microscopic images analysis showed that NaOCl acts efficiently on degradation of collagen fibrils for all adhesive systems. Conclusion: Aging in 10% NaOCl solution reduces bond strength and modifies the interfacial morphological characteristics of the adhesive systems tested.

The maxillo-mandibular facial complex may be affected by a variety of injuries that, although benign, present themselves locally aggressive. Treatment of these conditions have raised doubts as to choose the best therapy to be established, since the conservative treatment has been associated with high rates of recurrence, while the radical, but usually lead to a definitive cure, has created severe aesthetic - functional. In this context, adjuvant therapies, such as cryosurgery with liquid nitrogen, have been combined with conservative modalities with the aim of reducing the rate of recurrence without increasing its morbidity. The purpose of this study was to evaluate the effects induced by the application of liquid nitrogen in femoral diaphysis of rats. Were performed in femoral diaphysis of 42 rats, three local applications and sequential liquid nitrogen, interspersed with periods of 5 minutes, time of exposure that ranged from 1 or 2 minutes. After 1, 2, 4 and 12 weeks, the animals were sacrificed and the specimens were collected and processed and analyzed histomorphological and histomorphometrically. Histologically, the second week trial was a maximum of bone necrosis in both protocols. The depth and extent of bone necrosis average maximum induced by the Protocol of 1 minute was, respectively, 124,509 and ìm 2087.094 ìm, while that of 2 minutes were, respectively, 436424μm and 12046.426 micrometers. Based on the findings of this study, we can conclude that the protocol of 2 minutes produced a bone necrosis more pronounced than that of 1 minute, and therefore more suitable for the treatment of aggressive bone lesions covering the jaw.

O objetivo deste estudo foi avaliar in vitro e in situ os efeitos de um agente de limpeza cavitária a base de digluconato de clorexidina a 2% (CHX) na desinfecção de dentina cariada, bem como determinar a susceptibilidade de diferentes espécies a este agente antimicrobiano. Setenta blocos de dentina humana foram distribuídos de forma aleatória e submetidos a desafio cariogênico por um método microbiológico in vitro (n=15), bem como um in situ (n=20). No estudo in vitro, 30 blocos de dentina foram imersos por 5 dias, em caldo BHI inoculado com Streptococcus mutans, para indução de cárie. No estudo in situ, 20 voluntários usaram dispositivos palatinos contendo dois blocos de dentina, que foram gotejados com solução de sacarose 40%, 10 vezes ao dia, durante 14 dias. Ao final de cada período experimental, os blocos de dentina foram divididos aleatoriamente em dois grupos: Controle (solução de NaCl a 0,9%) e CHX. Amostras de dentina infectada foram coletadas antes e 5 min após cada tratamento, em seguida, as bactérias foram cultivadas e os microorganismos contados. Foram avaliados os seguintes microorganismos: estreptococos mutans in vitro e in situ, estreptococos totais, microorganismos viáveis totais e lactobacilos, in situ. A redução microbiana promovida por cada tratamento foi calculada e comparada entre os grupos pelo teste t, a susceptibilidade dos microorganismos isolados in situ foi comparada pela análise de variância ANOVA (= 5%). A redução microbiana promovida pela CHX foi significativamente maior quando comparada ao grupo controle para todos os microorganismos avaliados tanto in vitro quanto in situ. No entanto, não houve diferença na susceptibilidade dos vários microorganismos avaliados. Desta forma, a CHX foi capaz de reduzir a população microbiana em dentina infectada, sugerindo que esta abordagem pode ser uma ferramenta auxiliar para desinfecção de dentina cariada residual suprimindo o crescimento de microorganismos associados ao desenvolvimento de cárie.

Gutta-percha, in combination with a variety of sealers, is the most commonly used material for root canal filling. This association presents no adhesiveness to the root structure. Resilon cones and resinous cement (Epiphany) were introduced on the market that, in association with a self-conditioning primer, would alow a solid monoblock to be obtained. The Resilon/Epiphany system forms a monoblock within the canals that bonds to the dentin walls. It has potential to strengthen the walls against fracture. The material was proposed as an alternative to gutta-percha. The purpose of this in vitro study was to evaluate the fracture resistance of root canals filled with gutta-percha/ AH Plus and root canals filled with Resilon/Epipanhy system. Sixty extracted single rooted teeth were selected. The teeth were randomly categorized into 6 groups of 10 teeth each as follows: Group I: teeth without endodontic treatment; Group II: teeth were instrumented but without endodontic obturation; Group III: teeth were instrumented and obturated with gutta-percha in conjunction with AH Plus sealer and obturated with lateral condensation technique; Group IV: teeth were instrumented and obturated with gutta-percha in conjunction with AH Plus sealer and obturated with hybrid Tagger`s techinique; Group V: teeth were instrumented and obturated with Resilon/Epiphany system and obturated with lateral condensation technique; Group VI: teeth were instrumented and obturated with Resilon/Epiphany system and obturated with hybrid Tagger`s technique. The roots were submited to the compressive test. A Kratos Universal Testing Machine was used to apply a load to each specimen at a crosshead speed of 0,5mm per minute until the root fracture. The results were submited to ANOVA test ( 5%) and Tukey test. With respect to the fracture resistance there was no statiscally significant difference between the group filled with gutta-percha and the Resilon/Epiphany system. However, the group VI showed statistically significant difference when compared with group I and group II. The presence of the endodontic material is very important to maintenance the good fracture resistance, because the group II showed the worst results. The thermoplastic technique presented better results, but within statistically significant differences.

The aim of this in vitro study was to evaluate two adhesive systems: XP Bond (Dentsply) and Prime & Bond NT (Dentsply), applied on human tooth dentine with previous application of sodium hypochlorite (NaOCl) 10% and potassium oxalate (BisBlock - Bisco), by means of test of microtensile bond strength (µTBS), and standard of fracture analysis through optical microscope (OM). Thirty two non-carious human third molars were selected and had its oclusal enamel removed to produce flat dentin surface which was prepared using sandpapers (SiC) of granulation 600 through a politriz with the intention of standardize the smear layer. After that the teeth were divided in 8 groups: G1 (XP) - XP Bond; G2 (XPH) – 10% sodium hypochlorite + XP Bond; G3 (XPO) - potassium oxalate + XP Bond; G4 (XPHO) – 10% sodium hypochlorite + potassium oxalate + XP Bond; G5 (PB) - Prime & Bond NT; G6 (PBH) – 10% sodium hypochlorite + Prime & Bond NT; G7 (PBO) – potassium oxalate + Prime & Bond NT, e G8 (PBHO) – 10% sodium hypochlorite + potassium oxalate + Prime & Bond NT. After the treatments had been performed, crowns with resin composite Esthet X (Dentsply), color A-2 were built. These crowns were done through increments of 2 mm of thickness, with photo polymerization of 20 s for increment, until reaching 6 mm of height. The samples then had been parted for the attainment of beams with transversal section of 0.8 mm, to be performed under µTBS. The mechanical assay was carried through a machine of universal assay. The beams used in the microtensile test had been used later for the analysis of the standard of breaking through an OM. The results gotten in µTBS, Means(SD), were: XP – 35.225(15.470)Aa, XPH – 23.405(12.425)Ba, XPO – 15.492(9.168)Cb, XPHO – 16.389(11.108)Cb, PB – 27.589(11.265)Ab, PBH – 25.457(12.044)Aa, PBO – 31.631(14.391)Aa and PBHO – 26.263(8.912)Aa. After the values had been submitted to the statistical analysis (Kruskal-Wallis, Dunn e Mann-Whitney, α=0.05), was verified that XP Bond had better bond strength than Prime & Bond NT (control groups), and the 10% NaOCl treatment and potassium oxalate usage had decreased the bond strength of XP Bond and did not cause any statistical interference on Prime & Bond NT, even its usage was either together or isolated. The microscopic analysis of the breaking standard showed that almost all os specimens had adhesive fractures.

Aware that the main objective of endodontic treatment is the removal of microorganisms and the prevention of re-infection inside the root canal, and that the infections are polymicrobial and difficult to eliminate, the biomechanical preparation is essential for disinfection, though it is unable to eradicate all microorganisms. The intracanal medication is used as an adjunct to treatment, reducing the endodontic microbiota, and favoring the repair of periapical lesions. However, this dissertation consists of two papers and it is proposed, through a written review, to examine and discuss the intracanal medications most frequently used at present in endodontics - calcium hydroxide and chlorhexidine. Further, through research, to evaluate the antibacterial effect of biomechanical preparation and a calcium hydroxide based paste containing or not 2% chlorhexidine, as intracanal medication in the treatment of necrotic teeth after trauma, as well as to verify the presence of the microorganisms Fusobacterium nucleatum and black-pigmented bacilli inside the root canal of teeth. According to the inclusion criteria, the sample consisted of 14 incisors necrotic after trauma. The microbiological samples were acquired before (S1) and after biomechanical preparation (S2), after intracanal medication (S3) and 72 hours after removal of medication (S4). Selected at random, eight patients used calcium hydroxide as intracanal medication and six patients the calcium hydroxide based paste containing 2% chlorhexidine. The samples were collected sequentially, inserting three sterile absorbent paper cones with a diameter compatible with the root canal, and after a minute the paper points were removed and placed in a tube containing a reduced transport fluid, and sent to the laboratory for microbiological evaluation. The results were analyzed by the Friedman, Conover-Inman and Kruskal-Wallis tests (p <0.05). Microorganisms were found in 100 % of root canals in the initial samples (S1), while in S2 were detected in only 3 out of the 14 samples (21.4 %), resulting in a reduction in the number of colony forming units, a statistically significant result (p <0.001) between S1 and S2. No statistically significant reduction was observed when comparing S2 with S3, S2 with S4, and S3 with S4, regardless of the medication used. It was found that in S1, there was a predominance of Gram-positive cocci - 8 out of 14 (57.1 %) and Gram-negative cocci - 9 out of 14 (64.3 %). In S2 only Gram-positive bacterial morphotypes were detected, in 3 out of 14 samples (21.4 %) of Gram-positive cocci and 2 out of 14 (14.3%) of Gram-positive bacilli. The microorganisms Fusobacterium nucleatum found in 8 of the 14 samples (57.1%) and the black-pigmented bacilli found in 3 of the 14 (21.4%) of the initial samples, and were found in only one out of 6 (16.1%) samples taken after the use of calcium hydroxide. It was concluded that mechanical preparation of necrotic teeth after trauma, using 2.5% NaOCl, plays its role in significantly reducing the microbiota of root canals, but the calcium hydroxide, or the calcium hydroxide based paste containing 2% chlorhexidine, have a limited antibacterial effect, not being able to prevent the re-growth of bacteria after its use as an intracanal medication.

O objetivo deste trabalho foi validar para o Brasil o Child´s and Parent´s Questionnaire about Teeth Appearance e investigar a percepção e a preocupação devido à fluorose dentária em crianças de 12 anos de idade e nos seus pais. Este estudo foi realizado em duas regiões brasileiras: Piracicaba-SP, com ótimos níveis de flúor nas águas de abastecimento público, e Rafael Arruda-CE, com elevados teores de flúor in natura. O questionário original, que verifica o quanto nos últimos dois meses a criança sentiu-se incomodada, preocupada ou impedida de sorrir devido à aparência de seus dentes, ainda não havia sido validado para nenhuma outra língua que não aquelas em que foi originalmente desenvolvido (inglês e espanhol). Durante a primeira fase do estudo (adaptação semântica), obedeceu-se à seguinte metodologia: tradução, retrotradução, avaliação por um comitê de especialistas e pré-teste com 50 pares de pais/crianças. Na segunda fase (validação do instrumento), 213 crianças foram avaliadas clinicamente para o diagnóstico de fluorose dentária pelo índice de Dean, e responderam, assim como seus pais, ao questionário. Os dados obtidos na segunda fase foram usados para avaliar a confiabilidade (consistência interna e estabilidade temporal) e a validade (de constructo e de critério) do instrumento, utilizando coeficiente alfa de Cronbach, coeficiente de correlação intraclasse e correlação de Spearman. O teste t de Student para amostras independentes foi utilizado para a comparação entre as duas regiões, e o teste t pareado para a avaliação da concordância entre relatos de pais e filhos. Na primeira fase do estudo, nenhuma grande discrepância existiu entre as versões do instrumento (original, traduzida e retrotraduzida), e os ajustes realizados ocorreram mais em função dos níveis diversificados de escolaridade da população-alvo. Buscou-se utilizar vocabulário simples e frases curtas, e o questionário mostrou-se de fácil aplicação e bem aceito, permanecendo com os doze itens/subitens do original. Na segunda fase do estudo, a consistência interna foi aceitável e a estabilidade temporal de moderada a excelente. Houve correlação significativa entre percepção da fluorose moderada e severa e os dados clínicos, e entre percepção da fluorose e preocupações dos indivíduos. Embora os pais de Rafael Arruda-CE tenham tido uma maior percepção da fluorose, o incômodo e a preocupação com a aparência foram maiores em Piracicaba-SP. Pais e filhos tenderam a concordar em seus relatos, porém, quando discordaram, os pais geralmente se mostraram mais incomodados, preocupados e insatisfeitos com a aparência dentária do que as próprias crianças. Conclui-se que a versão brasileira do Child´s and Parent´s Questionnaire about Teeth Appearance é um instrumento válido e confiável para avaliar a percepção da estética dentária de crianças brasileiras e em seus pais. A percepção da fluorose teve um impacto negativo na satisfação com a estética dentária e levou à preocupação.

One of the aims of endodontic treatment is to promote the repair in the periapical region, from technical procedures including chemomechanical preparation, represented by the instrumentation associated to irrigation and aspiration, in addition to filling the root canal system. Thus, in Endodontics several irrigation solutions have been employed with the main functions of dentin walls lubrication, organic matter dissolution, removal of microorganisms and smear layer removal. Sodium hypochlorite is the most used substance, however, it possesses some disadvantages, such as high tissue toxicity. Others irrigation solution alternatives have been proposed, such as chlorhexidine and apple vinegar, which has suitable biocompatibility and ability to remove the smear layer. The root canal filling presents technical objectives, focused on the full sealing of the root canal system, as well as, biological, enabling closure of the apical foramen, through the deposition of mineralized tissue. For many years, gutta-percha associated with a sealer has been used, however, with the advent of adhesive materials in dental clinic, some hit the market with employment in Endodontics, the most known Resilon/Epiphany system. Thus, the objective of this study was to assess, by fluid filtration method, the influence of irrigation solution and the filling materials (cones and sealer) association in the apical root leakage. One hundred twelve lower pre-molars human teeth were instrumented and filled, being initially divided into two controls groups and 8 groups (n = 12), according to the irrigation solution, (H) sodium hypochlorite, (V) apple vinegar, and root canal filling materials, gutta-percha/AH Plus (GA), Resilon/Epiphany (RE), gutta-percha/Epiphany (GE) and Resilon/AH Plus (RA). The results have showed no statistical difference in relation to the irrigation solutions used (p> 0.05), nevertheless, it was found that the groups filled with Resilon/AH Plus (H/RA and V/RA) association had significantly more leakage than the other groups (p <0.05). It was concluded that the apical leakage were influenced only by the filling material regardless the irrigation solution.

The integration of titanium dental implants in bone has been reported extensively over the last few decades beginning with the original work of Branemark and co-workers. The use of titanium endosseous dental implants in the treatment of edentulous or partially edentulous patients has become an alternative to restore function and esthetics, however, this results depend on the quantity and quality of the maxillary or mandibular bone. Osteoporosis is a disease that influences the quality of bone tissue such that it may become susceptible to fracture. Significant relationship have been reported between oral bone and skeletal bone mass in postmenopausal women. Osteoporosis could, therefore be considered a risk factor for osseointegration of dental implants, but this is still controversial. Strontium ranelate is a new therapy for the treatment and prevention of osteoporosis that may dissociate bone formation and bone resorption by allowing continued production of bone while decreasing bone resorption. The purpose of this study was to determine the effect of systemic strontium ranelate therapy on early dental implant osseointegration based on torque-removal values in rabbits. Sixty-four identical titanium dental implants were placed using a standardized surgical protocol in the bilateral distal femur and proximal tibia of 16 New Zealand white rabbits (64 implants total). One week before implant placement, 8 rabbits were given doses of strontium ranelate (625mg/kg/day) until euthanized. The other 8 rabbits were untreated controls. One rabbit of each group were sacrificed in time of 15, 30, 45, 60, 75, 90, 105, 120 days, and torque-removal values were determined using a digital torque wrench for all implants. Analyses of torque data showed no statistical differences between the strontium ranelate and control groups. Based on the findings of this study, we can conclude that the time of 15 to 120 days of strontium ranelate administration does not interfere with the timing of early dental implant osseointegration in an animal model.

Malignant tumors of non-epithelial origin are considered rare in the head and neck region and they can show great morbidity and mortality. The aim of this study was to investigate the cases of sarcomas and melanomas in the head and neck region over the period from 1999 to 2008, in specialized centers located in the Municipality of Fortaleza. The data were collected from the register books of surgery of the head and neck and patient reports at the evaluated centers. Fifty-four cases were observed, being 36 sarcomas and 18 melanomas. As per the evaluation of the sarcomas, we have observed that the most assailed individuals were men with brown skin, ranging from 20 to 59 years old, with median age of 39.7. The relation man/woman was 1.7:1. The most prevailing histological type was the rhabdomyosarcoma, and the most attacked areas were the face and the cervical region. And as per the melanomas, adult men were also prevailing, ranging from 20 to 59 years old, with median age of 54.6. It has also been verified equal assailment in the brown and white races, with 33.3% in each one. The relation man/woman was 1.25:1. The most prevailing histological type was the superficial spreading melanoma, and the face skin was the most frequent location. In the evaluation of the origin, there was similarity in both diseases, being approximately half the patients in the capital city, and half in the state´s hinterland. As concerning the monitoring, the greatest part of the sample came from patients alive without evidence of the disease from the last consultation, corresponding to 41.6% in sarcomas and 44.5% in melanomas. The variation of therapy has also been observed in both groups, being the most common types of treatments, the association of surgery, radiotherapy and chemotherapy and surgery and radiotherapy for sarcomas and surgery, followed by surgery and radiotherapy for melanomas. Although malignant tumors of non-epithelial origin are rare in the head and neck region, they can show great morbidity and mortality and it is necessary the better understanding of their clinicalpatological aspects, in order to establish better treatment and life quality to these patients.