RCAAP Repository

Surgical Aspects of No-Touch Saphenous Vein Graft Harvesting in CABG: Clinical and Angiographic Follow-Up at 3 Months

Abstract With more than 800,000 coronary artery bypass grafting (CABG) operations annually worldwide and the saphenous vein being the most common conduit used, there is no question that improving saphenous vein graft patency is one of the most important tasks in CABG. This video describes the no-touch harvesting procedure of the saphenous vein on an 80-year old man with hypertension, hyperlipidemia and a previous myocardial infarction with percutaneous coronary intervention to the right coronary artery. He was complaining of exertional chest pain and was diagnosed with stable angina pectoris. The coronary angiography showed advanced three vessel disease with significant stenoses in the left anterior descending (LAD) artery, two marginal arteries (MAs) and the posterior descending artery (PDA), in addition to an occluded diagonal artery (DA). The patient received a triple sequential no-touch vein graft to the PDA and two MAs together with a double sequential no-touch vein graft to the DA and LAD. A vein graft was used to bypass the LAD due to the age of the patient and the low degree of stenosis in the LAD. The no-touch harvesting technique is described in detail in the film with complete narration. A follow-up of this patient was performed at three months both clinically and with a computed tomography angiography (CTA). No angina pectoris symptoms were reported by the patient and the wounds in the chest and lower limb were completely healed. The CTA showed patent no-touch saphenous vein grafts to all the distal anastomoses.

Year

2022-12-06T14:01:12Z

Creators

Samano,Ninos Pinheiro,Bruno Botelho Souza,Domingos

Long-Term Traumatic and Asymptomatic Aorto-Right Atrial Fistula

Abstract Aorto-atrial fistulas due to cardiac trauma are rare, and survivors require immediate surgical correction. Here, we report a case of an aorto-right atrial fistula due to penetrating trauma after a 16-year evolution, which developed symptoms of acute coronary syndrome and was treated with myocardial revascularization and correction of the aorto-cameral fistula.

Year

2022-12-06T14:01:12Z

Creators

Lima,Sandro Gonçalves de Lordsleem,Andréa Bezerra de Melo da Silveira Campos,Kaique Leal Silva,Juliana Guedes Santos,Marcelo Antônio Oliveira Markman Filho,Brivaldo

Congenital Aneurysm of the Right Atrium: Two Cases Report

Abstract Congenital aneurysm or enlargement of the right atrium is a rare condition. Two children operated on at the age of 14 months and 11 years old for congenital aneurysm of the right atrium are reported. Both presented cardiomegaly and symptoms of paroxysmal supraventricular tachycardia. Diagnosis was established by echocardiography. Surgical resection was successful. Both patients are free of symptoms and their chest X-ray and echocardiogram are normal. The first patient is now in her 17th postoperative year. The patients' evolution suggests that the surgery is a curative procedure.

Year

2022-12-06T14:01:12Z

Creators

Melo,Halyna Moraes Neto,Fernando Lapa,Cleusa Moraes,Carlos R.

Intracoronary Hydatid Cyst Resulted in Coronary Artery Disease in a Young Patient

Abstract Among all cystic echinococcosis cases, only 0.5%-2% exhibit a cardiac involvement. Only 10% of these become symptomatic. Considering the long time interval between the start of infestation and symptoms to occur, it is hard to diagnose cystic echinococcosis. When detected, even if it is asymptomatic, intramyocardial hydatid cyst requires surgical intervention due to risks of spontaneous rupture and anaphylaxis. In literature, no case of hydatid cyst located in the coronary arterial wall has been reported. Twenty-two-year-old male patient with previous history of pulmonary cystic echinococcosis was referred to us with typical symptoms of coronary artery disease. Coronary cineangiography revealed proximal left diagonal artery (LAD) occlusion. Pre-operative transthoracic echocardiography of the patient planned to undergo coronary artery bypass grafting unveiled an intracoronary calcified cystic mass. In operation, the calcified cystic mass with well-defined borders and size of 2x2 cm located within wall of proximal segment of the LAD artery was excised and double bypass with left internal thoracic artery (LITA) and great saphenous vein grafts to the LAD and first diagonal arteries, respectively, was done. Pathological analysis of the mass revealed it to be an inactive calcified hydatid cyst. Echinococcal IgG-ELISA test was positive. 12-week oral albendazole treatment (2x400 mg/day) was launched postoperatively and the patient was discharged on 7th postoperative day.

Year

2022-12-06T14:01:12Z

Creators

Vural,Unsal Aglar,Ahmet Arif Kayacioglu,İlyas

Ligature of the Left Main Coronary Artery after Surgery in Kawasaki Disease: Case Report

Abstract We report a case of a 23-year-old man who was diagnosed with Kawasaki disease that progressed to a coronary aneurysm in the left main coronary artery (LMA). He had suffered from acute coronary syndrome and then underwent an emergent percutaneous coronary angioplasty, in which a polyurethane-covered stent was placed inside the aneurysm. The stent was thrombosed one year later, despite the patient had been treated with anticoagulant and antiplatelet therapy. Emergency percutaneous intervention was then performed. LMA was reopened and stent malposition was observed. Therefore, urgent coronary bypass grafting was performed in which a high degree of competitive flow was observed through the reopened stent. LMA was ligated at the inflow of the aneurysm, resulting in an improvement of graft flow. Left main ligature has not been previously reported.

Year

2022-12-06T14:01:12Z

Creators

Barca,Laura Varela López-Menéndez,José Palacios,Ana Redondo Stuart,Jorge Rodríguez-Roda

Coronary Artery Dissection in a Patient with Buerger's Disease

Abstract Buerger's disease, vasculitis of small and medium-sized blood vessels, is a non-atherosclerotic and progressive occlusive condition which frequently involves the distal part of the limbs. The occlusion of coronary arteries in Buerger's disease is a rare condition; however, coronary artery dissection has not been reported previously. Therefore, this paper presents a 45-year-old man who developed coronary artery dissection associated with Buerger's disease. The patient was treated successfully with coronary artery bypass grafting with the left internal mammary artery to the left anterior descending artery, and saphenous vein graft to the right coronary artery.

Year

2022-12-06T14:01:12Z

Creators

Tekin,Ali İhsan Arslan,Ümit

Benefits of Fasting Abbreviation with Carbohydrates and Omega-3 Infusion During CABG: a Double-Blind Controlled Randomized Trial

Abstract Objective: To assess postoperative clinical data considering the association of preoperative fasting with carbohydrate (CHO) loading and intraoperative infusion of omega-3 polyunsaturated fatty acids (ω-3 PUFA). Methods: 57 patients undergoing coronary artery bypass grafting (CABG) were randomly assigned to receive 12.5% maltodextrin (200 mL, 2 h before anesthesia), (CHO, n=14); water (200 mL, 2 h before anesthesia), (control, n=14); 12.5% maltodextrin (200 mL, 2 h before anesthesia) plus intraoperative infusion of ω-3 PUFA (0.2 g/kg), (CHO+W3, n=15); or water (200 mL, 2 h before anesthesia) plus intraoperative infusion of ω-3 PUFA (0.2 g/kg), (W3, n=14). The need for vasoactive drugs was analyzed, in addition to postoperative inflammation and metabolic control. Results: There were two deaths (3.5%). Patients in CHO groups presented a lower incidence of hospital infection (RR=0.29, 95% CI 0.09-0.94; P=0.023), needed fewer vasoactive drugs during surgery and ICU stay (P<0.05); and had better blood glucose levels in the first six hours of recovery (P=0.015), requiring less exogenous insulin (P=0.018). Incidence of postoperative atrial fibrillation (POAF) varied significantly among groups (P=0.009). Subjects who receive ω-3 PUFA groups had fewer occurrences of POAF (RR=4.83, 95% CI 1.56-15.02; P=0.001). Patients in the W3 group had lower ultrasensitive-CRP levels at 36 h postoperatively (P=0.008). Interleukin-10 levels varied among groups (P=0.013), with the highest levels observed in the postoperative of patients who received intraoperative infusion of ω-3 PUFA (P=0.049). Conclusion: Fasting abbreviation with carbohydrate loading and intraoperative infusion of ω-3 PUFA is safe and supports faster postoperative recovery in patients undergoing on-pump CABG.

Year

2022-12-06T14:01:12Z

Creators

Feguri,Gibran Roder Lima,Paulo Ruiz Lúcio de Franco,Anna Carolina Cruz,Felipe Ramos Honorato De La Borges,Danilo Cerqueira Toledo,Laura Ramos Segri,Neuber José Aguilar-Nascimento,José Eduardo de

Relationship of Inter-Arm Systolic Blood Pressure Difference with Subclavian Artery Stenosis and Vertebral Artery Stenosis in Patients Undergoing Carotid Endarterectomy

Abstract Introduction: The aim of this study was to examine the association of inter-arm systolic blood pressure difference (IASBPD) with carotid artery stenosis, subclavian artery stenosis and vertebral artery stenosis in patients who underwent carotid endarterectomy. Methods: A total of 141 patients (29 females, 112 males; mean age 71.2±10.4 years; range 47 to 92 years) who underwent carotid endarterectomy between September 2010 and December 2017 were retrospectively evaluated. We classified patients into four groups according to the IASBPD ˂ 10 mmHg, ≥ 10 mm Hg, ≥ 20 mmHg and ≥ 30 mmHg. The stenosis of both subclavian and vertebral arteries was considered as ≥ 50%. Results: Of the 141 patients, 44 (31.2%) had ≥ 10 mmHg, 29 (20.5%) had ≥ 20 mmHg and 4 (2.8%) had ≥ 30 mmHg of IASBPD. 26 patients (18.4%) were diagnosed with significant subclavian artery stenosis and 18 (69.2%) of them had more than 20 mmHg of IASBPD. Of the 29 patients with IASBPD ≥ 20 mmHg, 19 patients (65.5%) had a significant subclavian artery stenosis. We found a significant correlation between preoperative symptoms and subclavian artery stenosis (P=0.018) and overall perioperative stroke was seen more frequently in patients with subclavian artery stenosis (P=0.041). A significant positive correlation was observed between vertebral artery stenosis and subclavian artery stenosis (P=0.01). Conclusion: Patients who were diagnosed with both subclavian artery stenosis and IASBPD (≥ 20 mmHg) had a higher risk of postoperative stroke and death, had higher total cholesterol, LDL-C, blood creatinine level, and were more symptomatic.

Year

2022-12-06T14:01:12Z

Creators

Deşer,Serkan Burç Yucel,Semih Murat Demirag,Mustafa Kemal Kolbakir,Fersat Keceligil,Hasan Tahsin

Coronary Artery Bypass Surgery in Brazil: Analysis of the National Reality Through the BYPASS Registry

Abstract Introduction: Coronary artery bypass grafting (CABG) is the most frequently performed heart surgery in Brazil. Recent international guidelines recommend that national societies establish a database on the practice and results of CABG. In anticipation of the recommendation, the BYPASS Registry was introduced in 2015. Objective: To analyze the profile, risk factors and outcomes of patients undergoing CABG in Brazil, as well as to examine the predominant surgical strategy, based on the data included in the BYPASS Registry. Methods: A cross-sectional study of 2292 patients undergoing CABG surgery and cataloged in the BYPASS Registry up to November 2018. Demographic data, clinical presentation, operative variables, and postoperative hospital outcomes were analyzed. Results: Patients referred to CABG in Brazil are predominantly male (71%), with prior myocardial infarction in 41.1% of cases, diabetes in 42.5%, and ejection fraction lower than 40% in 9.7%. The Heart Team indicated surgery in 32.9% of the cases. Most of the patients underwent cardiopulmonary bypass (87%), and cardioplegia was the strategy of myocardial protection chosen in 95.2% of the cases. The left internal thoracic artery was used as a graft in 91% of the cases; the right internal thoracic artery, in 5.6%; and the radial artery in 1.1%. The saphenous vein graft was used in 84.1% of the patients, being the only graft employed in 7.7% of the patients. The median number of coronary vessels treated was 3. Operative mortality was 2.8%, and the incidence of cerebrovascular accident was 1.2%. Conclusion: CABG data in Brazil provided by the BYPASS Registry analysis are representative of our national reality and practice. This database constitutes an important reference for indications and comparisons of therapeutic procedures, as well as to propose subsequent models to improve patient safety and the quality of surgical practice in the country.

Year

2022-12-06T14:01:12Z

Creators

Paez,Rodrigo Pereira Hossne Junior,Nelson Américo Santo,José Amalth do Espírito Berwanger,Otavio Santos,Renato Hideo Nakagawa Kalil,Renato Abdala Karam Jatene,Fabio B. Cavalcanti,Alexandre Biasi Zilli,Alexandre Cabral Bettiati Jr,Luiz Carlos Figueira,Fernando Augusto Marinho dos Santos D'Azevedo,Stephanie Steremberg Pires Soares,Marcelo José Ferreira Fernandes,Marcio Pimentel Ardito,Roberto Vito Bogdan,Renata Andrea Barberio Campagnucci,Valquíria Pelisser Nakasako,Diana Rodrigues,Clarissa Garcia Rodrigues Junior,Anilton Bezerra Cascudo,Marcelo Matos Atik,Fernando Antibas Lima,Elson Borges Nina,Vinicius José da Silva Heluy,Renato Albuquerque Azeredo,Lisandro Gonçalves Henrique Junior,Odilon Silva Mendonça,José Teles de Silva,Katharina Kelly de Oliveira Gama Pandolfo,Marcelo Lima Júnior,José Dantas de Faria,Renato Max Santos,Jonas Gonçalves dos Coelho,Guilherme Henrique Biachi Pereira,Sergio Nunes Senger,Roberta Buffolo,Enio Caputi,Guido Marco Oliveira,Juliana Aparecida Borges de Gomes,Walter J.

Effect of Preoperative Creatinine Levels on Mortality after Coronary Artery Bypass Grafting Surgery: an Observational Study

Abstract Introduction: Renal function is an independent risk factor for mortality among on-pump coronary bypass grafting (ONCABG) patients. This association is well known in the international literature, but there is a lack of knowledge of how admission creatinine (AC) levels modulate each cardiovascular risk factor. Objective: The aim of this paper was to assess the effect of different AC levels on mortality among ONCABG patients. Methods: 1,599 patients who underwent ONCABG between December 1999 and February 2006 at Hospital de Base in São José do Rio Preto/SP-Brazil were included. They were divided into quartiles according to their AC levels (QI: 0.2 ≤AC < 1.0 mg/dL; QII: 1.0 ≤ AC < 1.2 mg/dL; QIII: 1.2 ≤ AC < 1.4 mg/dL; and QIV: 1.4 ≤ AC ≤ 2.6 mg/dL). Seven risk factors were then evaluated in each stratum. Results: Mortality was higher in the QIV group than QI or QII groups. Factors such as age (≥ 65 years) and cardiopulmonary bypass (CPB) time (≥ 115 minutes) in QIV, as well preoperative hospital stay (≥ 5 days) in QIII, were associated with higher mortality rates. Creatinine variation greater than or equal to 0.4 mg/dL increased mortality rates in all groups. The use of intra-aortic balloon pump and dialysis increased mortality rates in all groups except for QII. Type I neurological dysfunction increased the mortality rate in the QII and III groups. Conclusion: Creatinine levels play an important role in ONCABG mortality. The combination of selected risk factors and higher AC values leads to a worse prognosis. On the other hand, lower AC values were associated with a protective effect, even among elderly patients and those with a high CPB time.

Year

2022-12-06T14:01:12Z

Creators

Oliveira,Marcos Aurélio Barboza de Santos,Carlos Alberto dos Brandi,Antônio Carlos Dotta,Ana Helena Botelho,Paulo Henrique Husseini Godoy,Moacir Fernandes de Braile,Domingo M.

The Expression of and Preoperative Correlation between Heat-Shock Protein 70, EuroSCORE, and Lactate in Patients undergoing CABG with Cardiopulmonary Bypass

Abstract Objetive: Coronary artery bypass grafting (CABG) with cardiopulmonary bypass (CPB) improved symptoms and increased survival and quality of life in patients with coronary artery disease. However, it should be the main cause of a complex organic systemic inflammatory response that greatly contributes to several postoperative adverse effects. Methods: We aimed to evaluate heat-shock protein 70 (HSP 70) expression as a morbimortality predictor in patients with preserved ventricular function undergoing coronary artery bypass grafting (CABG) with cardiopulmonary bypass (CPB) and to determine their association with the lactate as a marker of tissue hypoperfusion and the EuroSCORE risk score. This is a prospective, observational study including 46 patients and occurring between May and July 2016. Patients without ventricular dysfunction undergoing myocardial revascularization with extracorporeal circulation were included. They were divided into (1) complicated and (2) uncomplicated postoperative evolution groups. EuroSCORE, lactate levels, and HSP 70 expression and their correlations were determined. Results: Statistical analysis showed that the group with complicated evolution had higher EuroSCORE values than the other group. HSP 70 protein levels were significantly increased in the group with uncomplicated evolution and showed similar results. According to our results, HSP family proteins may be independent predictors of uncomplicated evolution in patients without ventricular dysfunction undergoing CABG with CPB. Conclusion: HSP 70 should be a good discriminator and protection marker for complications in cardiac surgery.

Year

2022-12-06T14:01:12Z

Creators

Cantero,Marcos Antonio Almeida,Rui Manuel Siqueira Morato,Priscila Neder Santos-Junior,Valfredo de Almeida Moura,Carolina Soares Amaya-Farfan,Jaime Fonseca,João Luis Lollo,Pablo Christiano Barboza

Diagnostic Performance of QFR for the Evaluation of Intermediate Coronary Artery Stenosis Confirmed by Fractional Flow Reserve

Abstract Introduction: Quantitative flow ratio (QFR) is a novel method enabling efficient computation of FFR from three-dimensional quantitative coronary angiography (3D QCA) and thrombolysis in myocardial infarction (TIMI) frame counting. We decided to perform a systematic review and quantitative meta-analysis of the literature to determine the correlation between the diagnosis of functionally significant stenosis obtained by QFR versus FFR and to determine the diagnostic accuracy of QFR for intermediate coronary artery stenosis. Methods: We searched PubMed, Embase, and Web of Science for studies concerning the diagnostic performance of QFR. Our meta-analysis was performed using the DerSimonian and Laird random effects model to determine sensitivity, specificity, positive likelihood ratio (LR+), negative likelihood ratio (LR-), and diagnostic odds ratio (DOR). The sROC was used to determine diagnostic test accuracy. Results: Nine studies consisting of 1175 vessels in 1047 patients were included in our study. The pooled sensitivity, specificity, LR+, LR-, and DOR for QFR were 0.89 (95% CI: 0.86-0.92), 0.88 (95% CI: 0.86-0.91), 6.86 (95% CI,: 5.22-9.02), 0.14 (95% CI: 0.10-0.21), and 53.05 (95% CI: 29.75-94.58), respectively. The area under the summary receiver operating characteristic (sROC) curve for QFR was 0.94. Conclusion: QFR is a simple, useful, and noninvasive modality for diagnosis of functional significance of intermediate coronary artery stenosis.

Year

2022-12-06T14:01:12Z

Creators

Xing,Zhenhua Pei,Junyu Huang,Jiabing Hu,Xinqun Gao,Shan

Previous Cardiac Surgery: a Predictor of Mortality in Aortic Valve Replacement?

Abstract Introduction: Previous cardiac surgery (PCS) is a risk factor for operative mortality in pa-tients undergoing reoperative aortic valve replacement (AVR) and may be influenced by the volume of patients in each center. The aim of this study was to evaluate the results of AVR in patients with previous cardiac surgery in a low volume cardiac center (400 cases per year). Methods: Between January 2006 and December 2016, 854 patients underwent isolated AVR surgery at our institution. Of these, 70 had PCS. Propensity match (PM) was per-formed to balance basal covariates. Operative mortality and survival were the primary outcomes. Results: The PCS and first-time surgery (FTS) groups had significant differences in base-line characteristics (PCS group were older, higher incidence of hypertension, endocarditis, NYHA III/IV, lower LVEF, higher creatinine and higher EuroSCORE). In the unmatched population, patients with PCS had higher operative mortality (17.1% vs. 4.6%, P=0.001). In the PM groups, this difference was not significant (12.5% and 3.6%, P=0.08). The only independent predictors for operative mortality found in the PCS group were age and fe-male gender. Age and diabetes were identified as the only independent predictors of sur-vival. Conclusion: PCS was not a predictor for operative mortality nor long-term survival in pa-tients undergoing isolated aortic valve replacement.

Year

2022-12-06T14:01:12Z

Creators

Dayan,Victor Arocena,Maria José Fernandez,Amparo Silva,Eloísa Zerpa,Diego Pérez

Postoperative Atrial Fibrillation: Evaluation of its Economic Impact on the Costs of Cardiac Surgery

Abstract Objective: The objective of this study was to calculate the direct costs of postoperative atrial fibrillation (POAF) in a high-complexity cardiovascular hospital. Methods: We performed a cost analysis with a pairwise-matched design. Twenty-two patients with POAF and 22 patients without this complication were included. Pair-matching was performed (1:1) based on the following criteria: identical type of surgery, similar EuroSCORE II values, and absence of any other postoperative complication. Results: The total hospital cost was significantly higher in the POAF group than in the non-POAF group (US$ 10,880 [± 2,688] vs. US$ 8,856 [± 1,782], respectively, for each patient; P=0.005). This difference was attributable to postoperative costs (US$ 3,103 [± 1,552] vs. US$ 1,238 [± 429]; P=0.0001) for patients with or without POAF, respectively. The median postoperative lengths of stay were 9 (range 5-17) and 5 (3-9) days for patients with and without POAF (P=0.032), respectively. Preoperatively, no differences were found in the EuroSCORE II values (median 1.7 vs. 1.6, respectively; P=0.91) or direct costs (US$ 1,127 vs. US$ 1,063, respectively; P=0.56) between POAF and non-POAF groups. Conclusion: POAF generates a high economic burden in the overall costs of cardiac surgery, and our results reveal the differential contribution of each of the evaluated factors. This information, which was previously unavailable in this setting, is essential for the development of more effective prevention strategies.

Year

2022-12-06T14:01:12Z

Creators

Hernández-Leiva,Edgar Alvarado,Paula Dennis,Rodolfo José

Left Ventricular Aneurysm Repair: Off-pump Linear Plication versus On-pump Patch Plasty

Abstract Objective: The study aimed to compare the clinical outcomes of simplified linear plication and classic patch plasty in patients with left ventricular aneurysm (LVA). Methods: We retrospectively reviewed 282 patients undergoing LVA repair between 2006 and 2016. After propensity score matching, 45 pairs of patients receiving LVA surgery were divided into either a patch group (on-pump endoventricular patch plasty) or a plication group (off-pump linear plication). Then, their early surgical outcomes and long-term survival were compared in two matched groups. Results: The heart function improvement at discharge was similar in the two matched groups, while patients in the patch group more commonly suffered from low cardiac output syndrome (P=0.042) with higher proportion of intra-aortic balloon pumping assistance (P=0.034) than patients in the plication group. Compared with patients in the patch group, the patients in the plication group had shorter recovery times, regarding to mechanical ventilation, intensive care unit stay, and hospital stay (P<0.001, P<0.001, and P=0.001, respectively). No significant difference was found in the long-term survival (P=0.62). Conclusions: Off-pump linear plication presented acceptable results in terms of early outcomes and long-term survival. For high-risk patients, the simplified LVA repair technique may be an option.

Year

2022-12-06T14:01:12Z

Creators

Wei,Hua Chai,Shoudong Liu,Changcheng Huang,Xinsheng Gu,Chengxiong

Treatment of Pericardial Effusion Through Subxiphoid Tube Pericardiostomy and Computerized Tomography- or Echocardiography - Guided Percutaneous Catheter Drainage Methods

Abstract Objective: In this retrospective study, we aimed to observe the efficacy of pericardial effusion (PE) treatments by a survey conducted at the Department of Cardiovascular Surgery, Faculty of Medicine, Atatürk University. Methods: In order to get comparable results, the patients with PE were divided into three groups - group A, 480 patients who underwent subxiphoid pericardiostomy; group B, 28 patients who underwent computerized tomography (CT)-guided percutaneous catheter drainage; and group C, 45 patients who underwent echocardiography (ECHO)-guided percutaneous catheter drainage. Results: In the three groups of patients, the most important symptom and physical sign were dyspnea and tachycardia, respectively. The most common causes of PE were uremic pericarditis in patients who underwent tube pericardiostomy, postoperative PE in patients who underwent CT-guided percutaneous catheter drainage, and cancer-related PE in patients who underwent ECHO-guided percutaneous catheter drainage. In all the patients, relief of symptoms was achieved after surgical intervention. There was no treatment-related mortality in any group of patients. In patients with tuberculous pericarditis, the rates of recurrent PE and/or constrictive pericarditis progress were 2,9% and 2,2% after tube pericardiostomy and ECHO-guided percutaneous catheter drainage, respectively. Conclusion: Currently, there are many methods to treat PE. The correct treatment method for each patient should be selected according to a very careful analysis of the patient's clinical condition as well as the prospective benefit of surgical intervention.

Year

2022-12-06T14:01:12Z

Creators

Colak,Abdurrahim Becit,Necip Kaya,Ugur Ceviz,Munacettin Kocak,Hikmet

Medidas antropométricas como preditoras de fatores de risco cardiovascular na população urbana do Irã

FUNDAMENTO: O sobrepeso e a obesidade são um importante problema de saúde pública na sociedade pela sua associação com diversas doenças crônicas. OBJETIVO: O objetivo deste estudo é determinar a prevalência e a distribuição de sobrepeso e obesidade, usando diferentes medidas antropométricas, e identificar o melhor indicador antropométrico intimamente relacionado aos fatores de risco de Doenças Cardiovasculares (DCV) em população iraniana urbana. MÉTODOS: O presente estudo transversal foi realizado com 991 homens e 1.188 mulheres de 15 a 64 anos. Foram medidos Índice de Massa Corporal (IMC), Circunferência Abdominal (CA), Relação Cintura-Quadril (RCQ), Relação Cintura-Altura (RCA) e porcentagem de gordura corporal. Foi obtida amostra de sangue em jejum. Foram avaliados os fatores de risco cardiovascular, incluindo glicemia de jejum, triglicerídeos, colesterol total (col-T), colesterol de baixa densidade (LDL-colesterol) e colesterol da lipoproteína de alta densidade (HDL-colesterol). RESULTADOS: Em relação ao IMC, 49% dos homens e 53% das mulheres estavam acima do peso ou obesos, e 10,2% dos homens e 18,6% das mulheres encontravam-se obesos. Tanto nos homens quanto nas mulheres, a prevalência de sobrepeso esteve maior entre aqueles com 40-49 anos de idade, e a prevalência de obesidade esteve maior entre aqueles com 50 anos ou mais. Usando a análise de regressão múltipla, IMC, RCA e RCQ explicaram o maior percentual de variação de triglicerídeos, razão entre col-T e HDL-colesterol e LDL-colesterol em homens, respectivamente, ao passo que RCQ explicou o maior percentual de variação de triglicerídeos e CA explicou o maior percentual de variação da razão entre col-T e HDL-colesterol e LDL-colesterol em mulheres. CONCLUSÃO: Nossos dados indicam que RCQ e RCA foram os indicadores antropométricos que melhor previram fatores de risco cardiovascular em homens e RCQ e CA, em mulheres.

Year

2022-12-06T14:01:12Z

Creators

Gharakhanlou,Reza Farzad,Babak Agha-Alinejad,Hamid Steffen,Lyn M. Bayati,Mahdi

Prevalência e preditores de embolia pulmonar em pacientes com insuficiência cardíaca agudamente descompensada

FUNDAMENTO: Não existe descrição da prevalência de Embolia Pulmonar (EP) em pacientes internados por quadro clássico de Insuficiência Cardíaca descompensada (IC). OBJETIVO: Em pacientes internados por IC, (1) descrever a prevalência de EP, e (2) avaliar a acurácia diagnóstica dos Escores de Wells e de Genebra. MÉTODOS: Pacientes internados primariamente por IC realizaram sistematicamente cintilografia pulmonar de ventilação/perfusão, sendo EP definida por laudo de alta probabilidade. Para fins de interpretação, definimos baixa probabilidade clínica de EP como prevalência < 5%, de acordo com dados da literatura. No cálculo do tamanho amostral, 49 pacientes seriam necessários para fornecer um intervalo de confiança 95% com ± 10% de precisão, estimando uma prevalência a priori de 15%. RESULTADOS: Em 51 pacientes estudados, seis apresentaram cintilografia de alta probabilidade, resultando em prevalência de 12% (95% IC = 5% - 23%). Os Escores de Wells e de Genebra apresentaram área abaixo da curva ROC de 0,53 (95% IC = 0,27 - 0,80; p = 0,80) e 0,43 (95% IC = 0,13 - 0,73; p = 0,56), respectivamente, indicando ausência de acurácia para o diagnóstico de EP. Alternativamente, variáveis relacionadas à IC mostraram tendência a associação com EP e um modelo exploratório formado por esse tipo de variável apresentou acurácia diagnóstica para EP (ROC = 0,81; 95% IC = 0,66 - 0,96; p = 0,01). CONCLUSÃO: (1) A despeito da ausência de suspeita primária, pacientes internados com IC possuem probabilidade clínica intermediária de EP concomitante; (2) Os escores usualmente utilizados para estimar a probabilidade clínica de EP não se aplicam à população com IC e futuros modelos preditores devem contemplar variáveis relacionadas a esta síndrome.

Year

2022-12-06T14:01:12Z

Creators

Correia,Luís C. L. Góes,Creuza Ribeiro,Hysla Cunha,Manuela Paula,Rogério de Esteves,J. Péricles

Medida do átrio esquerdo em pacientes com suspeita de insuficiência cardíaca com fração de ejeção normal

FUNDAMENTO: O modelo fisiopatológico da insuficiência cardíaca com fração de ejeção normal (ICFEN) está centrado na presença de disfunção diastólica, o que ocasiona mudanças estruturais e funcionais no átrio esquerdo (AE). A medida do tamanho do AE pode ser utilizada como um marcador da presença de ICFEN, sendo um indicador da elevação crônica da pressão de enchimento do VE, cuja mensuração é de fácil obtenção. OBJETIVO: Estimar a acurácia da medida do tamanho do AE, utilizando os valores indexados do diâmetro e do volume do AE para o diagnóstico de ICFEN em pacientes ambulatoriais. MÉTODOS: Estudamos 142 pacientes (67,3 ± 11,4 anos, 75% de mulheres) com suspeita de IC, os quais foram divididos em dois grupos: com ICFEN (n = 35) e sem ICFEN (n = 107). RESULTADOS: A função diastólica, avaliada pelo ecodopplercardiograma, mostrou diferença significativa entre os dois grupos em relação aos parâmetros que avaliaram o relaxamento ventricular (E' 6,9 ± 2,0 cm/s vs. 9,3 ± 2,5 cm/s - p < 0,0001) e a pressão de enchimento do VE (relação E/E' 15,2 ± 6,4 vs. 7,6 ± 2,2 - p < 0,0001). O ponto de coorte do volume do AE indexado (VAE-I) de 35 mL/m² foi o que melhor se correlacionou com o diagnóstico de ICFEN, demonstrando sensibilidade de 83%, especificidade de 83% e acurácia de 83%. Já o ponto de coorte do diâmetro ântero-posterior do AE indexado (DAE-I) de 2,4 cm/m² apresentava sensibilidade de 71%, especificidade de 66% e acurácia de 67%. CONCLUSÃO: Para o diagnóstico de ICFEN em pacientes ambulatoriais, o VAE-I é o método mais acurado em comparação ao DAE-I. Na avaliação ecocardiográfica, a medida do tamanho do AE deveria ser substituída pela medida indexada do volume. (Arq Bras Cardiol. 2011; [online].ahead print, PP.0-0)

Year

2022-12-06T14:01:12Z

Creators

Jorge,Antônio José Lagoeiro Ribeiro,Mario Luiz Rosa,Maria Luiza Garcia Licio,Fernanda Volponi Fernandes,Luiz Cláudio Maluhy Lanzieri,Pedro Gemal Jorge,Bruno Afonso Lagoeiro Brito,Flavia Oliveira Xavier Mesquita,Evandro Tinoco

Automedida da pressão arterial para o controle das cifras tensionais e para a adesão ao tratamento

FUNDAMENTO: A medida da pressão arterial (PA) pelo próprio paciente, sem protocolos rígidos, com treinamento adequado, aparelhos validados e no próprio domicílio, é definida como automedida da pressão arterial (AMPA). OBJETIVO: Avaliar a interferência da AMPA na adesão ao tratamento e no controle pressórico. MÉTODOS: Participaram do estudo 57 pacientes, 38 no grupo de estudo (GE) e 19 no grupo de controle (GC). Esses pacientes foram seguidos por 12 meses e avaliados na randomização (V1), bem como no sexto (V2) e no décimo segundo mês (V3). Comparadas as médias da PA pela medida casual, pela AMPA e pela monitorização ambulatorial da pressão arterial (MAPA), exames laboratoriais e as respostas ao questionário sobre o estilo de vida. Os aparelhos utilizados foram: OMRON HEM 714, para a AMPA; OMRON 705 CP, para a medida casual; e Monitor SPACELABS 9002, para a MAPA. RESULTADOS: A idade média em anos foi de 62,05 ± 10,78 e de 55,42 ± 11,87 no GE e no GC (p = 0,03), respectivamente. Os valores da pressão arterial sistólica (PAS) pela medida casual no GE e no GC foram: 140,01 ± 16,73 mmHg e 141,79 ± 23,21 mmHg em V1 (p = 0,72); 135,49 ± 12,73 mmHg e 145,69 ± 19,31 mmHg em V2 (p = 0,02); 131,64 ± 19,28 mmHg e 134,88 ± 23,21 mmHg em V3 (p = 0,59). Os valores da pressão arterial diastólica (PAD) foram: 84,13 ± 10,71 mmHg e 86,29 ± 10,35 mmHg em V1 (p = 0,47); 81,69 ± 10,88 mmHg e 89,61 ± 11,58 mmHg em V2 (p = 0,02); 80,31 ± 11,83 mmHg e 86 ± 13,38 mmHg em V3 (p = 0,12). CONCLUSÃO: Os pacientes do GE apresentaram adesão ao tratamento não farmacológico semelhante ao GC, mas tiveram maior adesão ao tratamento medicamentoso e utilizaram menor número de drogas anti-hipertensivas. Não houve diferença entre os grupos na comparação do perfil metabólico e da função renal. (Arq Bras Cardiol. 2011; [online].ahead print, PP.0-0)

Year

2022-12-06T14:01:12Z

Creators

Souza,Weimar Kunz Sebba Barroso Jardim,Paulo César Brandão Veiga Brito,Ludmila Porto Araújo,Fabrício Alves Sousa,Ana Luíza Lima