RCAAP Repository
A circulação e o uso do PISA em Portugal: o que dizem os políticos
No summary/description provided
Role of inflammatory/immune response and cytokine polymorphisms in the severity of Chronic Hepatitis C (CHC) before and after Direct Acting Antiviral (DAAS) treatment
Host regulatory immune response is involved in the hepatic inflammatory process caused by the hepatitis C virus (HCV). We aimed to determine if HCV clearance with direct-acting antivirals (DAAs) changes the hepatic fibrosis stage, biochemical parameters of liver injury, and inflammatory/immune responses. Sample: 329 chronic hepatitis C (CHC) patients, 134 of them treated with DAAs. Liver fibrosis was evaluated by transient elastography (FibroScan), biochemical and cellular parameters were determined by standard methods, cytokine concentration by enzyme-linked immunoabsorbent assay (ELISA), and genetic polymorphisms by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) or endpoint genotyping. Before DAA treatment, severe fibrosis or cirrhosis (F3/4) was associated with higher values of tumor necrosis factor-alpha (TNF-α) and genotypes transforming growth factor-beta-509 C/T_CC (TGF-β-509 C/T_CC), interleukine-10-1082 T/C_CC (IL-10-1082 T/C_CC), and IL-10-592 G/T_GT. After DAA treatment, fewer F3/4 patients and lower values of TNF-α were found. Patients with TNF-α-308 G/A_GG and IL-10-592 G/T_GT were at risk for F3/4. Lack of improvement of liver fibrosis was associated with lower baseline values of platelet count for genotypes TNF-α-308 G/A_GG and haplotype TT/GG of IL-10-1082 T/C and IL-10-592 G/T. Our study showed decreased liver fibrosis/inflammation and normalization of liver injury biomarkers after DAA treatment. It also points to the importance of suppressing the pro-inflammatory response by DAAs in the resolution of hepatitis C, contributing to the improvement of liver damage evaluated by transient elastography.
2023
Ferreira, Joana Oliveira, Mariana Bicho, Manuel Serejo, Fátima
Global impact of the COVID-19 pandemic on stroke volumes and cerebrovascular events
Background and objectives: Declines in stroke admission, IV thrombolysis (IVT), and mechanical thrombectomy volumes were reported during the first wave of the COVID-19 pandemic. There is a paucity of data on the longer-term effect of the pandemic on stroke volumes over the course of a year and through the second wave of the pandemic. We sought to measure the effect of the COVID-19 pandemic on the volumes of stroke admissions, intracranial hemorrhage (ICH), IVT, and mechanical thrombectomy over a 1-year period at the onset of the pandemic (March 1, 2020, to February 28, 2021) compared with the immediately preceding year (March 1, 2019, to February 29, 2020). Methods: We conducted a longitudinal retrospective study across 6 continents, 56 countries, and 275 stroke centers. We collected volume data for COVID-19 admissions and 4 stroke metrics: ischemic stroke admissions, ICH admissions, IVT treatments, and mechanical thrombectomy procedures. Diagnoses were identified by their ICD-10 codes or classifications in stroke databases. Results: There were 148,895 stroke admissions in the 1 year immediately before compared with 138,453 admissions during the 1-year pandemic, representing a 7% decline (95% CI [95% CI 7.1-6.9]; p < 0.0001). ICH volumes declined from 29,585 to 28,156 (4.8% [5.1-4.6]; p < 0.0001) and IVT volume from 24,584 to 23,077 (6.1% [6.4-5.8]; p < 0.0001). Larger declines were observed at high-volume compared with low-volume centers (all p < 0.0001). There was no significant change in mechanical thrombectomy volumes (0.7% [0.6-0.9]; p = 0.49). Stroke was diagnosed in 1.3% [1.31-1.38] of 406,792 COVID-19 hospitalizations. SARS-CoV-2 infection was present in 2.9% ([2.82-2.97], 5,656/195,539) of all stroke hospitalizations. Discussion: There was a global decline and shift to lower-volume centers of stroke admission volumes, ICH volumes, and IVT volumes during the 1st year of the COVID-19 pandemic compared with the prior year. Mechanical thrombectomy volumes were preserved. These results suggest preservation in the stroke care of higher severity of disease through the first pandemic year.
2023
Nguyen, Thanh N. Qureshi, Muhammad M. Klein, Piers Yamagami, Hiroshi Mikulik, Robert Czlonkowska, Anna Abdalkader, Mohamad Sedova, Petra Sathya, Anvitha Lo, Hannah C. Mansour, Ossama Yassin Iversen, Helle Klingenberg Truelsen, Thomas Clement Wienecke, Troels Sobh, Khalid Ylikotila, Pauli Alpay, Kemal Strbian, Daniel Bernady, Patricia Casenave, Philippe Dan, Maria Vanguru, Husitha Reddy Faucheux, Jean-Marc Gentric, Jean-Christophe Magro, Elsa Sabben, Candice Reiner, Peggy Rouanet, Francois Bohmann, Ferdinand O. Boskamp, Stefan Mbroh, Joshua Nagel, Simon Lesaine, Emilie Nolte, Christian H. Ringleb, Peter A. Rosenkranz, Michael Poli, Sven Thomalla, Götz Karapanayiotides, Theodoros Koutroulou, Ioanna Kargiotis, Odysseas Palaiodimou, Lina Barrientos Guerra, Jose Dominguo Tsivgoulis, Georgios Huded, Vikram Menon, Bindu Nagendra, Shashank Prajapati, Chintan Sylaja, P.N. Krishna Pramana, Nyoman Angga Sani, Achmad Firdaus Ghoreishi, Abdoreza Farhoudi, Mehdi Hokmabadi, Elyar Sadeghi Loochtan, Aaron I. Raya, Tariq Abu Kalmanovich, Shani Avnery Ronen, Levite Sabetay, Sergiu Ionut Acampa, Maurizio Adami, Alessandro Castellan, Lucio Longoni, Marco Ornello, Raffaele Renieri, Leonardo Demeestere, Jelle Bigliani, Claudia Rolla Romoli, Michele Sacco, Simona Salmaggi, Andrea Sangalli, Davide Zini, Andrea Doijiri, Ryosuke Fukuda, Hiroki Fujinaka, Toshiyuki Fujita, Kyohei Uchino, Ken Imamura, Hirotoshi Sakai, Nobuyuki Kanamaru, Takuya Kimura, Naoto Kono, Ryuhei Miyake, Kosuke Sakaguchi, Manabu Sakai, Kenichiro Sonoda, Kazutaka Todo, Kenichi Inoa, Violiza Miyashita, Fumio Tokuda, Naoki Matsumaru, Yuji Matsumoto, Shoji Ohara, Nobuyuki Shindo, Seigo Takenobu, Yohei Yoshimoto, Takeshi Toyoda, Kazunori Uwatoko, Takeshi Goyal, Nitin Yagita, Yoshiki Yamada, Takehiro Yamamoto, Nobuaki Yamamoto, Ryoo Yazawa, Yukako Sugiura, Yuri Waweru, Peter Kuria Baek, Jang-Hyun Lee, Si Baek Seo, Kwon-Duk Charidimou, Andreas Sohn, Sung-Il Arsovska, Anita Ante Chan, Yong Chieh Wan Zaidi, Wan Asyraf Jaafar, Ainul Syahrilfazli Gongora-Rivera, Fernando Martinez-Marino, Manuel Infante-Valenzuela, Adrian Groppa, Stanislav Leahu, Pavel Siegler, James E. Coutinho, Jonathan M. Rinkel, Leon A. Dippel, Diederik W.J. van Dam-Nolen, Dianne H.K. Ranta, Annemarei Wu, Teddy Y. Adebayo, Tajudeen Temitayo Bello, Abiodun H. Nwazor, Ernest Okwundu Sunmonu, Taofiki Ajao Yaghi, Shadi Wahab, Kolawole Wasiu Ronning, Ole Morten Sandset, Else Charlotte Al Hashmi, Amal M. Ahmad, Saima Rashid, Umair Rodriguez-Kadota, Liliana Vences, Miguel Ángel Yalung, Patrick Matic Hao Dy, Jon Stewart de Sousa, Diana Aguiar Pineda-Franks, Maria Carissa Co, Christian Oliver Brola, Waldemar Debiec, Aleksander Dorobek, Malgorzata Karlinski, Michal Adam Labuz-Roszak, Beata M. Lasek-Bal, Anetta Sienkiewicz-Jarosz, Halina Staszewski, Jacek Mohammaden, Mahmoud H. Sobolewski, Piotr Wiacek, Marcin Zielinska-Turek, Justyna Araujo, Andre Pinho Rocha, Mariana Castro, Pedro Cruz, Vitor Tedim Ferreira, Paulo Venancio Ferreira, Patricia Nunes, Ana Paiva Haussen, Diogo C. Fonseca, Luisa Marto, João Pedro Melo, Teresa Pinho e Rodrigues, Miguel Silva, M. Luis Dimitriade, Adela Falup-Pecurariu, Cristian Hamid, May Adel Venketasubramanian, Narayanaswamy Krastev, Georgi Kristoffersen, Espen Saxhaug Mako, Miroslav Ayo-Martin, Oscar Hernández-Fernández, Francisco Blasco, Jordi Rodríguez-Vázquez, Alejandro Cruz-Culebras, Antonio Moniche, Francisco Montaner, Joan Perez-Sanchez, Soledad García Sánchez, María Jesús Lereis, Virginia Pujol Guillán Rodríguez, Marta Jood, Katarina Nordanstig, Annika Mazya, Michael V. Moreira, Tiago T.P. Bernava, Gianmarco Beyeler, Morin Bolognese, Manuel Carrera, Emmanuel Dobrocky, Tomas Scollo, Sergio Daniel Karwacki, Grzegorz Marek Keller, Emanuela Hsieh, Chang Yang Boonyakarnkul, Surawan Churojana, Anchalee Aykac, Ozlem Ozdemir, Atilla Özcan Bajrami, Arsida Senadim, Songul Hussain, Syed Irteza Campbell, Bruce C. V. John, Seby Banerjee, Soma Kwan, Joseph Krishnan, Kailash Lenthall, Robert Matthews, Ashok Wong, Ken Zhang, Liqun Altschul, Dorothea Asif, Kaiz S. Ma, Alice Bahiru, Zeelalem Below, Kristine Biller, José Ruland, Sean Chaudry, Saqib A. Chen, Michael Chebl, Alex Cibulka, Jackie Cistrunk, Leon Clark, Judith Thomas, James Orton Colasurdo, Marco Czap, Alexandra de Havenon, Adam D'Amato, Salvatore Dharmadhikari, Sushrut Grimmett, Kasey B. Dmytriw, Adam A. Etherton, Mark R. Ezepue, Chizoba Farooqui, Mudassir Parsons, Mark W. Feske, Steven K. Fink, Lauren Gasimova, Ulviyya Guzik, Amy K. Hakemi, Maryam Hovingh, Majesta Khan, Muhib Jillela, Dinesh Kan, Peter T. Khatri, Rakesh Singhal, Shaloo Khawaja, Ayaz M. Khoury, Naim N. Kiley, Nicole L. Kim, Benny S. Kolikonda, Murali K. Kuhn, Anna Luisa Lara, Stephanie Linares, Guillermo Linfante, Italo Lukovits, Timothy G. Slater, Lee-Anne Lycan, Sarah Male, Shailesh S. Maali, Laith Mancin, John Masoud, Hesham Mohamed, Ghada A. Monteiro, Andre Nahab, Fadi Nalleballe, Krishna Ortega-Gutierrez, Santiago Tomazini Martins, Rodrigo Puri, Ajit S. Radaideh, Yazan Rahangdale, Rahul H. Rai, Ansaar Ramakrishnan, Pankajavalli Reddy, Aravind B. Rojas-Soto, Diana M. Romero, Jose Rafael Rost, Natalia S. Rothstein, Aaron Enzinger, Chris Omran, Setareh Salehi Sheth, Sunil A. Siddiqui, Adnan H. Starosciak, Amy K. Tarlov, Nicholas E. Taylor, Robert A. Wang, Michael J. Wolfe, Jared Wong, Ka-Ho Le, Huynh Vu Gattringer, Thomas Nguyen, Quy Viet Pham, Thong Nhu Nguyen, Trung Thanh Phan, Hoang Thi Ton, Mai Duy Fischer, Urs Michel, Patrik Strambo, Davide Martins, Sheila O. Zaidat, Osama O. Rahman, Aminur Nogueira, Raul G. Bonnet, Thomas Ligot, Noemie De Raedt, Sylvie Lemmens, Robin Vanacker, Peter Vandervorst, Fenne Conforto, Adriana Bastos Hidalgo, Raquel C.T. de Oliveira Neves, Luciana Martins, Rodrigo Targa Mora Cuervo, Daissy Liliana Rebello, Leticia C. Santiago, Igor Bessa Lameirinhas da Silva, Isabelle Sakelarova, Teodora Kalpachki, Rosen Alexiev, Filip Catanese, Luciana Cora, Elena Adela Goyal, Mayank Hill, Michael D. Kelly, Michael E. Khosravani, Houman Lavoie, Pascale Peeling, Lissa Pikula, Aleksandra Rivera, Rodrigo Chen, Hui-Sheng Chen, Yimin Huo, Xiaochuan Miao, Zhongrong Yang, Shuiquan Bedekovic, Marina Roje Bralic, Marina Budincevic, Hrvoje Corredor-Quintero, Angel Basilio Lara-Sarabia, Osvaldo E. Cabal, Martin Tenora, Dusan Fibrich, Petr Herzig, Roman Hlaváčová, Helena Hrabanovska, Emanuela Hlinovsky, David Jurak, Lubomir Kadlcikova, Jana Karpowicz, Igor Klecka, Lukas Kovar, Martin Lauer, David Neumann, Jiri Palouskova, Hana Reiser, Martin Rekova, Petra Rohan, Vladimir Skoda, Ondrej Škorňa, Miroslav Sobotková, Lenka Sramek, Martin Zakova, Lenka Christensen, Hanne Drenck, Nicolas
Embracing monogenic Parkinson's disease: the MJFF Global Genetic PD Cohort
Background: As gene-targeted therapies are increasingly being developed for Parkinson's disease (PD), identifying and characterizing carriers of specific genetic pathogenic variants is imperative. Only a small fraction of the estimated number of subjects with monogenic PD worldwide are currently represented in the literature and availability of clinical data and clinical trial-ready cohorts is limited. Objective: The objectives are to (1) establish an international cohort of affected and unaffected individuals with PD-linked variants; (2) provide harmonized and quality-controlled clinical characterization data for each included individual; and (3) further promote collaboration of researchers in the field of monogenic PD. Methods: We conducted a worldwide, systematic online survey to collect individual-level data on individuals with PD-linked variants in SNCA, LRRK2, VPS35, PRKN, PINK1, DJ-1, as well as selected pathogenic and risk variants in GBA and corresponding demographic, clinical, and genetic data. All registered cases underwent thorough quality checks, and pathogenicity scoring of the variants and genotype-phenotype relationships were analyzed. Results: We collected 3888 variant carriers for our analyses, reported by 92 centers (42 countries) worldwide. Of the included individuals, 3185 had a diagnosis of PD (ie, 1306 LRRK2, 115 SNCA, 23 VPS35, 429 PRKN, 75 PINK1, 13 DJ-1, and 1224 GBA) and 703 were unaffected (ie, 328 LRRK2, 32 SNCA, 3 VPS35, 1 PRKN, 1 PINK1, and 338 GBA). In total, we identified 269 different pathogenic variants; 1322 individuals in our cohort (34%) were indicated as not previously published. Conclusions: Within the MJFF Global Genetic PD Study Group, we (1) established the largest international cohort of affected and unaffected individuals carrying PD-linked variants; (2) provide harmonized and quality-controlled clinical and genetic data for each included individual; (3) promote collaboration in the field of genetic PD with a view toward clinical and genetic stratification of patients for gene-targeted clinical trials. © 2023 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
2023
Vollstedt, Eva‐Juliane Schaake, Susen Lohmann, Katja Padmanabhan, Shalini Brice, Alexis Lesage, Suzanne Tesson, Christelle Vidailhet, Marie Wurster, Isabel Hentati, Faycel Mirelman, Anat Zhang, Bao‐rong Garraux, Gaetan Chung, Sun Ju Kim, Yun Joong Winkelmann, Juliane Sue, Carolyn M. Tan, Eng‐King Damásio, Joana Klivényi, Péter Kostic, Vladimir S. Giladi, Nir Arkadir, David Martikainen, Mika Borges, Vanderci Hertz, Jens Michael Brighina, Laura Spitz, Mariana Suchowersky, Oksana Riess, Olaf Das, Parimal Mollenhauer, Brit Marder, Karen Gatto, Emilia M. Petersen, Maria Skaalum Hattori, Nobutaka Wu, Ruey‐Meei Illarioshkin, Sergey N. Valente, Enza Maria Aasly, Jan O. Aasly, Anna Alcalay, Roy N. Thaler, Avner Waters, Cheryl Farrer, Matthew J. Brockmann, Kathrin Corvol, Jean‐Christophe Klein, Christine Fahn, Stanley Kasten, Meike Brüggemann, Norbert Borsche, Max Foroud, Tatiana Tolosa, Eduardo Garrido, Alicia Annesi, Grazia Gagliardi, Monica Bozi, Maria Stefanis, Leonidas Ferreira, Joaquim J Correia Guedes, Leonor Avenali, Micol Petrucci, Simona Clark, Lorraine Fedotova, Ekaterina Y. Abramycheva, Natalya Y. Alvarez, Victoria Menéndez‐González, Manuel Jesús Maestre, Silvia Gómez‐Garre, Pilar Mir, Pablo Belin, Andrea Carmine Ran, Caroline Lin, Chin‐Hsien Kuo, Ming‐Che Crosiers, David Wszolek, Zbigniew K. Ross, Owen A. Jankovic, Joseph Nishioka, Kenya Funayama, Manabu Clarimon, Jordi Williams‐Gray, Caroline H. Camacho, Marta Cornejo‐Olivas, Mario Torres‐Ramirez, Luis Wu, Yih‐Ru Lee‐Chen, Guey‐Jen Morgadinho, Ana Pulkes, Teeratorn Termsarasab, Pichet Berg, Daniela Kuhlenbäumer, Gregor Kühn, Andrea A. Borngräber, Friederike de Michele, Giuseppe De Rosa, Anna Zimprich, Alexander Puschmann, Andreas Mellick, George D. Dorszewska, Jolanta Carr, Jonathan Ferese, Rosangela Gambardella, Stefano Chase, Bruce Markopoulou, Katerina Satake, Wataru Toda, Tatsushi Rossi, Malco Merello, Marcelo Lynch, Timothy Olszewska, Diana A. Lim, Shen‐Yang Ahmad‐Annuar, Azlina Tan, Ai Huey Al‐Mubarak, Bashayer Hanagasi, Hasmet Koziorowski, Dariusz Ertan, Sibel Genç, Gençer de Carvalho Aguiar, Patricia Barkhuizen, Melinda Pimentel, Marcia M.G. Saunders‐Pullman, Rachel van de Warrenburg, Bart Bressman, Susan Toft, Mathias Appel‐Cresswell, Silke Lang, Anthony E. Skorvanek, Matej Boon, Agnita J.W. Krüger, Rejko Sammler, Esther M. Tumas, Vitor
How to optimize the adherence to a guideline-directed medical therapy in the secondary prevention of cardiovascular diseases: a clinical consensus statement from the European Association of Preventive Cardiology
A key factor to successful secondary prevention of cardiovascular disease (CVD) is optimal patient adherence to treatment. However, unsatisfactory rates of adherence to treatment for CVD risk factors and CVD have been observed consistently over the last few decades. Hence, achieving optimal adherence to lifestyle measures and guideline-directed medical therapy in secondary prevention and rehabilitation is a great challenge to many healthcare professionals. Therefore, in this European Association of Preventive Cardiology clinical consensus document, a modern reappraisal of the adherence to optimal treatment is provided, together with simple, practical, and feasible suggestions to achieve this goal in the clinical setting, focusing on evidence-based concepts.
2023
Pedretti, Roberto F. E. Hansen, Dominique Ambrosetti, Marco Back, Maria Berger, Thomas Ferreira, Mariana Cordeiro Cornelissen, Véronique Davos, Constantinos H. Doehner, Wolfram de Pablo y Zarzosa, Carmen Frederix, Ines Greco, Andrea Kurpas, Donata Michal, Matthias Osto, Elena Pedersen, Susanne S. Salvador, Rita Esmeralda Simonenko, Maria Steca, Patrizia Thompson, David R. Wilhelm, Matthias Abreu, Ana
As ânforas de tipo D de Pellicer de Castro Marim – da II Idade do Ferro até à Época Republicana
As ânforas D de Pellicer, como um objecto de estudo, apresentam alguma complexidade, devido à sua diversidade formal, tornando, em alguns casos, difícil a sua identificação ou correspondência a uma variante morfológica previamente identificada. De modo geral, trata-se de um recipiente anfórico de produção tradicionalmente conhecida como «Turdetana», e que, de acordo com a sua recolha em vários contextos arqueológicos, apresenta uma grande diacronia temporal, desde a II Idade do Ferro até à Época Romana Republicana. Algumas diferenças morfológicas a nível do bordo e as associações contextuais permitiram a diferenciação em dois grupos: Pré-romanas (Idade do Ferro), datadas a partir dos finais do século IV a.C., e Evolucionadas (Romano-Republicano), com datação compreendida entre os séculos II e I a.C.. No Castelo de Castro Marim, exemplares deste tipo de ânfora foram recolhidos em contextos bem datados, tendo-se criado as condições necessárias para aprofundar o conhecimento sobre estes contentores e a sua evolução morfológica. Por outro lado, o estudo levado a efeito nesta dissertação acrescenta dados para avaliar a importância do sítio no âmbito do comércio do Ocidente, concretamente das relações que se estabelecem entre o litoral algarvio, a área do Guadalquivir e da baía gaditana.
Ética e narrativa: valores éticos incorporados nas obras para crianças de Sophia de Mello Breyner Andresen
Sophia de Mello Breyner Andresen é uma das mais importantes escritoras portuguesas do século XX e no discurso da sua literatura infantil destaca-se a ligação à estética e à ética. O presente trabalho visa investigar como Sophia conseguia revelar e apoiar certos juízos estéticos e éticos através da sua literatura infantil, e observar como os seus contos podem exercer uma persistente influência. Este trabalho concentra-se em oito contos infantis de Sophia todos publicados no século XX. Com o intuito de contextualizar o objeto de estudo deste trabalho, na primeira parte, começa-se por organizar e fazer um resumo sobre a contextualização histórica da evolução da literatura infantil em Portugal, a infância de Sophia, e a relação entre os valores éticos e produção da literatura infantil. Neste contexto, na segunda parte, com o objetivo de entender a abordagem da escritora ao colocar os juízos éticos no seu mundo literário, observam-se e interpretam-se os elementos narrativos, incluindo os espaços, as personagens e o tempo, investigando como esses elementos conferem aos textos as mudanças e os significados temáticos no enredo e o seu papel na transmissão dos valores éticos. Ao mesmo tempo, salienta-se a inspiração e o reconto das histórias tradicionais e disponíveis, seguindo o padrão das histórias tradicionais, a literatura infantil de Sophia herda a característica da imprecisão temporal. Por último, a propósito da transmissão dos valores éticos e da aceitação da narrativa da literatura infantil de Sophia, analisam-se a comunicação ética e moral e as características temáticas das obras. A escritora usou uma linguagem poetizada nos seus contos infantis para indicar o oposto da linguagem infantilizada, ao mesmo tempo usando uma linguagem de moral com o intuito de transmitir os valores universais às crianças, através de uma intenção moralizante, dando um conjunto de regras de ação como referência. Para além da atitude criativa perante a natureza física e de outros temas fundadas nos valores compartilhados, a procura e a luta pela justiça e pela igualdade social também pertencem aos temas mais importantes nos contos de Sophia.
Care-oriented occupations' devaluation and their relationship with profit and production
Healthcare, Early Education and Domestic (HEED) occupations are less socially valued than Science, Technology, Engineering and Mathematics (STEM) occupations. Social psychologists have predominantly focused on HEED occupations being typically female and communal, while STEM occupations are typically male and agentic. We propose that the caring nature of HEED work itself may play a role in its devaluation. With female liberation, this work migrated from the private sphere towards being monetized, while not offering means of production on which modern society is based on. Thus, we suggest that not conforming to profit and production norms may be at the core of the devaluation of HEED occupations. Study 1 aimed at exploring whether the care orientation of HEED occupations readily comes to people’s minds. In a free association task, participants (N = 64) wrote 3 words related to each of 18 different occupations in HEED, STEM, and filler fields. As expected, HEED occupations elicited more care-related words than the other occupations. In Study 2, we manipulated how the impact of a HEED or STEM occupation was described in a text: economic versus well-being impact. After reading the text, participants (N = 143) rated several aspects of the occupation (e.g., ideal income, perceived status, difficulty, professionals’ attributes). Results replicated previous findings relating to occupational stereotypes and social perception models. Contrary to our expectations, our manipulation did not lead to more positive ratings or higher compensation. Our findings suggest that care labour may be damaged by heightened perceptions of profit and that general communal orientations benefit both communal workers and society at large. Future research could expand on these findings through exploration of the agentic versus collective efforts in a similar design and through furthering the social perception of communion, emotional expression and emotional intelligence in the workplace.
A construção do humor nos textos das publicações do site de notícias “isento de verdade” Sensacionalista
Esta tese apresenta um estudo dos recursos de construção de humor, pela perspectiva da Análise do Discurso, por meio da análise dos textos publicados pelo jornal Sensacionalista, o qual é denominado pela excêntrica isenção da verdade. O contexto histórico de uso da ideia de humor é apresentado, desde o emprego do termo relacionado à definição com base na Medicina, até a abordagem filosófica e psicológica que viabilizam à Linguística, área em que se enquadra esta tese, aplicar conceitos ao plano da construção de quebras de expectativas em textos. O humor é inserido no plano teórico da Análise do Discurso por meio da relação dialógica demarcada por Benveniste e polifônica, por Ducrot. Tais informações permitem apresentar a pluralidade de pontos de vista que revelam a escora de parte do que é o humor. Além disso, essa abordagem conduz a pesquisa à contribuição de Maingueneau sobre o indissociável vínculo do humor com seu contexto social tanto de produção como de circulação. É na relação entre as informações do texto com humor e seu contexto que a cena enunciativa permite a investigação desenvolvida aqui. A pesquisa conduz o estudo do humor pela construção da ideia de que ele é resultado de uma incongruência, ou quebra de expectativa. Para compreender a composição desse desvio, esta tese baseia-se na Teoria do Roteiro Semântico do Humor, “Semantic-Script Theory of Humor” (SSTH) proposta inicialmente por Raskin e desenvolvida na Teoria Geral do Humor Verbal, a “General Theory of Verbal Humor” (GTVH), proposta também por Raskin junto com Attardo. Nessa contextura, a GTVH apresenta o processo de triangulação e de seis parâmetros para identificação do humor, metodologia desenvolvida na análise de textos do Senssacionalista ao longo desta pesquisa, permitindo a identificação de regularidades linguísticas que, sobre o tema do humor, revelam sua complexidade e requinte articulatório, relacionado a contextos sociais, culturais, históricos linguísticos e pragmáticos. Assim, o humor é aqui compreendido como um interessante e envolvente tema explorado linguisticamente e compreendido discursivamente pelas incongruências que se realizam como resultado de um conjunto intrigante de relações cognitivas.
Weekly external load performance effects on sports injuries of male professional football players
One of the most challenging issues professional football players face throughout their careers is injuries. Those injuries often result from suboptimal training programs that were not designed according to the players' individual needs. This prospective study aimed to examine in detail the effects of sports injuries on professional football players' weekly external load performances. Thirty-three male professional football players were monitored using 10-Hz Global Positioning System (GPS) units (Apex pro series, StatSports) during an entire season. The variables considered in the analysis were total distance (TD), high-speed running (HSR), accelerations (ACC), and decelerations (DEC). The comparisons were made between the four-week block before injury (-4T), four-week block after return (+4T), and players' season averages (S). Players displayed significantly higher values of TD, HSR, ACC, and DEC in the -4T, compared to the other two moments (+4T and S). Furthermore, the comparison between the +4T and S showed no significant variations in the GPS metrics. It was shown that a significant increase in players' weekly external load performance over a four-week period may have a negative effect on the occurrence of injuries from a professional football standpoint. Future research should consider the effects of injury severity on players' external load variations.
2023
Martins, Francisco Marques, Adilson França, Cíntia Sarmento, Hugo Henriques, Ricardo Ihle, Andreas de Maio Nascimento, Marcelo Saldanha, Carolina Przednowek, Krzysztof Gouveia, Elvio
Past history shapes evolution of reproductive success in a global warming scenario
Adaptive evolution is critical for animal populations to thrive in the fast-changing natural environments. Ectotherms are particularly vulnerable to global warming and, although their limited coping ability has been suggested, few real-time evolution experiments have directly accessed their evolutionary potential. Here, we report a long-term experimental evolution study addressing the evolution of Drosophila thermal reaction norms, after ∼30 generations under different dynamic thermal regimes: fluctuating (daily variation between 15 and 21 °C) or warming (daily fluctuation with increases in both thermal mean and variance across generations). We analyzed the evolutionary dynamics of Drosophila subobscura populations as a function of the thermally variable environments in which they evolved and their distinct background. Our results showed clear differences between the historically differentiated populations: high latitude D. subobscura populations responded to selection, improving their reproductive success at higher temperatures whereas their low latitude counterparts did not. This suggests population variation in the amount of genetic variation available for thermal adaptation, an aspect that needs to be considered to allow for better predictions of future climate change responses. Our results highlight the complex nature of thermal responses in face of environmental heterogeneity and emphasize the importance of considering inter-population variation in thermal evolution studies.
2023
Santos, Marta A. Antunes, Marta Grandela, Afonso Carromeu-Santos, Ana Quina, Ana S. Santos, Mauro Matos, Margarida Simões, Pedro
O PISA na literatura científica: um caso de propagação, recriação e contestação de conhecimento
No summary/description provided
O sistema de informação arquivística da Comissão do Mercado de Capitais de Angola
Um dos objetivos do estudo é apresentar a gestão da informação como ativo estratégico das organizações, sobretudo no âmbito do contexto da transição digital, posicionando os arquivistas como indispensáveis em qualquer organização como elementos que operam pela garantia de pleno acesso a informação com qualidade, rapidez e eficácia, para além de promover e manter a preservação de todo a informação no longo prazo. Este estudo pretende contribuir para que a Comissão do Mercado de Capitais de Angola adote as melhores práticas da gestão da informação e a sua boa divulgação relativa à proteção adequada da informação, tendo presente o seu valor probatório e informativo, e disso deem conta aos profissionais da informação. Fixa um conjunto de princípios e recomendações e medidas concretas que estão internacionalmente estabelecidos e consubstanciados em documentos de gestão, de modo a tornar mais eficaz e eficiente o SI, e que conduzem a uma boa governança das sociedades e das instituições que produzem informação, quer em suporte analógico, quer em suporte digital. Deste modo, seleciona como objeto de estudo o Sistema de Informação Arquivística da CMC de Angola, incluindo o arquivo analógico e digital orientada pela seguinte pergunta de partida: “De que modo a redefinição do Sistema de Informação Arquivística na CMC poderá potenciar a gestão da informação?”. Para esta investigação, são definidos dois objetivos: Situar o sistema de informação arquivística no seio das organizações e analisar como o sistema de informação pode ser viável no cumprimento da missão institucional da CMC; e (Re)definir um modelo de integração do sistema de informação arquivística, analógico e digital, no sistema de informação da CMC. O estudo, de natureza qualitativa, assenta no método da Investigação documental, situando-se no campo disciplinar da gestão da informação, bem com a apresentação das boas práticas da informação para que a CMC possa ser (re) estruturada com base em orientações e sugestões, que não são certamente alheias aos contextos nacional e internacional no desenvolvimento da Ciência da Informação. Este estudo permite concluir, que a modernização administrativa da CMC passa necessariamente pela implementação de um sistema de informação com gestão integrada da informação baseada em processos.
2022
Quental, Miraldina Wanga da Silva José Correia do
A central place foraging seabird flies at right angles to the wind to jointly optimize locomotor and olfactory search efficiency
To increase the probability of detecting odour plumes, and so increase prey capture success, when winds are stable central place foraging seabirds should fly crosswind to maximize the round-trip distance covered. At present, however, there is no empirical evidence of this theoretical prediction. Here, using an extensive GPS tracking dataset, we investigate, for the first time, the foraging movements of Bulwer's petrels (Bulweria bulwerii) in the persistent North Atlantic trade winds. To test the hypotheses that, in stable winds, petrels use crosswind to maximize both the distance covered and the probability of detecting olfactory cues, we combine state-space models, generalized additive models and Gaussian plume models. Bulwer's petrels had the highest degree of selectivity for crosswinds documented to date, often leading to systematic zig-zag flights. Crosswinds maximized both the distance travelled and the probability of detecting odour plumes integrated across the round-trip (rather than at any given point along the route, which would result in energetically costly return flight). This evidence suggests that petrels plan round-trip flights at departure, integrating expected costs of homeward journeys. Our findings, which are probably true for other seabirds in similar settings, further highlight the critical role of wind in seabird foraging ecology.
2022
Ventura, Francesco Catry, Paulo Dias, Maria P. Breed, Greg A. Folch, Arnau Granadeiro, José Pedro
Examining the Socioeconomic Benefits of Oysters: A Provisioning Ecosystem Service from the Mangroves of Guinea-Bissau, West Africa
In Guinea-Bissau, West Africa, extensive patches of mangrove provide important resources for the subsistence of local populations. The objective of this work was to assess the relevance of oyster harvesting, consumption, and trade for local communities. For that purpose, a qualitative approach derived from rural diagnostic methodologies was applied in two coastal protected areas where extensive areas of mangrove are present. Ten animal species were found to be collected there by women, both for household consumption and for sale. The oyster, Crassostrea tulipa is the only species harvested in all the 12 inquired villages and, by far, the most available in local markets. Three types of oyster products are commercialized—fresh oysters with shell, fresh oysters without shell, and dry oysters—with the latter being the most traded and valued. These products are marketed in the villages, in local markets, and in the capital, Bissau, as well as exported to Senegal. The harvesting of oysters is practised during 20 weeks per year, providing households with an average annual income of 580–595€. This income, which represents a large proportion of the yearly income, is mostly managed by women and is used to cover basic family expenses, namely, to meet the needs of children. This study uncovers the socioeconomic benefits derived from a specific mangrove ecosystem service, which is directly used by coastal human communities, and highlights the importance of oysters for food security, for empowering women, and for securing household incomes.
2022
Dias, Giselle Alvarenga Vasconcelos, Maria José Catarino, Luís
Pharmacognostic Survey on Paeonia Broteri – An Iberian Endemism
The genus Paeonia (Paeoniaceae) includes perennial plants distributed throughout the northern hemisphere and some of these are used in traditional medicine and cultivated as ornamental species. Paeonia broteri is endemic to Iberian Peninsula and the current paper is the first report on a pharmacognostic survey on its roots, leaves and corresponding powders. Using light and scanning electron microscopy, simple and compound polyhedral starch grains, with a fissure-type hilum and no striae, are recorded in the root phelloderm cells and the presence of idioblasts with druse-type calcium oxalate crystals, in addition to isolated stone cells, are also common. Irregular and sinuous epidermal cells can be detected on both leaf surfaces and anomocytic stomata, with an elliptical-rounded shape, are only on the abaxial face. In leaves, druse-type calcium oxalate crystals appear along the vascular tissues. The histochemical tests allowed the in situ localization of some chemical groups and the most relevant detected were polyphenols and terpenoids.
Size does matter: intraspecific geometric morphometric analysis of wings of the blowfly Chrysomya albiceps (Diptera: Calliphoridae)
Blowflies have forensic, sanitary and veterinary importance, as well as being pollinators, parasitoids and ecological bioindicators. There is still little work with real data and from experiments assessing the relationship between blowflies’ morphologic features and environmental and demographic factors. The present work tests whether the variation, in the shape and size, of Chrysomya albiceps (Wiedemann, 1819) wings is influenced by the following factors: 1) time; 2) temperature; 3) sex and; 4) different types of carcasses (pig, dog/cat and whale). Male and female wings from four different sites collected in six different years were used to obtain wing size and shape of C. albiceps. Analyses between wing shape and the variables tested had low explanatory power, even though they had statistical support. However, it was possible to identify differences in wing shape between males and females, with good returns in sex identification. The comparison between wing size and the variables tested showed that wing size has a negative relationship with temperature, significant differences between sexes, slight variation over time and no influence by carcass types. Furthermore, wing size influenced wing shape. Understanding population-specific characteristics of C. albiceps provide important insights about how the species reacts under specific conditions.
2022
Rodrigues-Filho, Sérgio J.M. Prado e Castro, Catarina Lopes, Luís Filipe da Fonseca, Isabel Pereira Rebelo, Maria Teresa
New national and regional bryophyte records, 69
No summary/description provided
2022
Ellis, L. T. Afonina, O. M. Czernyadjeva, I. V. Alegro, A. Šegota, V. Boiko, M. Zagorodniuk, N. Burghardt, M. Alataş, M. Aslan, G. Batan, N. Dragićević, S. Erata, H. Kırmacı, M. Özenoğlu, H. Evangelista, M. Valente, E. B. Feletti, T. A. Ezer, T. Fedosov, V. E. Fuertes, E. Oliván, G. Natcheva, R. Gospodinov, G. Hodgson, A. Kiebacher, T. Köckinger, H. von Konrat, M. Krajšek, S. S. Cimerman, Ž. L. Kučera, J. Mikulášková, E. Müller, F. Muñoz, J. Ochyra, R. Peralta, D. F. Philippe, M. Porley, R. D. Rawat, K. K. Paul, R. R. Ros, R. M. Werner, O. Schäfer-Verwimp, A. Sergio, Cecilia Shkurko, A. V. Söderström, L. de Souza, A. M. Spitale, D. Ștefănuţ, S. Tabua, M. Winter, G.
Revealing the foraging movements and diet of the White-faced Storm Petrel Pelagodroma marina in the NE Atlantic
The White-faced Storm Petrel (WFSP) Pelagodroma marina has a widespread distribution, although virtually nothing is known about their feeding ecology and distributions at-sea. To describe their foraging areas, a total of 77 birds were equipped with 1 g-GPS loggers on Selvagem Grande, Madeira, Portugal (30° 09′ N, 15° 52′ W), during the 2018 and 2019 breeding seasons. We also assessed the diet of WFSP by analysing 17 faecal samples from chicks and 1 regurgitation from an adult using DNA metabarcoding techniques. Additionally, we collected body feathers from ten WFSP chicks to determine mercury concentration. WFSP fed mainly in deep oceanic waters, travelling up to 400 km from the colony, and did not concentrate in any well-defined, population-level foraging hotspots. Some individuals foraged along the edge of the shelf, near the African coast and the Canary Islands, especially during chick rearing. The duration of foraging trips and the total distance travelled, were, on average, 5.1 days and 723 km during the incubation period and 3.0 days and 578 km during chick rearing. The diet of WFSP was dominated by fish and cephalopods (crustacean prey were not detected), with Myctophidae (FO = 71%) representing the main fish family. WFSP often consume mesopelagic fish, in line with their preference for deep oceanic waters and with a small difference in at sea behavior (i.e., travel speed) between the diurnal and nocturnal period. The relatively high concentrations of mercury accumulated in body feathers of WFSP chicks (3.45 ± 1.44 mg kg−1 dry weight; range 1.68–6.01 mg kg−1) support the idea that WFSP raise their chicks mostly on mesopelagic prey from deep pelagic areas.
2022
Alho, Maria Catry, Paulo Silva, Monica C. Nunes, Vera L. Granadeiro, José P.
A novel combination of methods identifies priority conservation areas for an endemic California Current seabird
There are growing pressures on marine biodiversity. Seabirds in particular are one the most-threatened groups. The black-vented shearwater (Puffinus opisthomelas) is endemic to Mexican islands and the only shearwater living its entire life cycle in the California Current System, one of the most productive large marine ecosystems in the world. Marine Protected Areas (MPAs) in this region, however, were designed without consideration of accurate data on seabird distributions. Here, 57 black-vented shearwaters were GPS-tracked from their main breeding colony (95% of the global population) over four seasons (2016–2019) to estimate their at-sea distribution. Two methods were applied to identify priority conservation areas: the approach developed by BirdLife International to identify marine Important Bird and Biodiversity Areas and a method using expectation-maximization binary clustering to identify core foraging areas. One potential marine Important Bird and Biodiversity Area close to the breeding colony and five core foraging areas were identified. These priority conservation areas were largely beyond the bounds of the current MPA network in the region. Our results detail opportunities for improving the implementation of conservation and management measures in the California Current System region with respect to seabirds. The approach of combining site identification methods can be applied to other seabird species for which high-resolution tracking data are available and can help guide conservation action plans and MPA design.
2022
Soldatini, Cecilia Albores‐Barajas, Yuri V. Rosas‐Hernandez, Martha P. Handley, Jonathan Beal, Martin Dias, Maria P. Dell'omo, Giacomo