RCAAP Repository
Jean Salem (org.), L’atomisme aux XVIIe et XVIIIe siècles, Paris, Publications de la Sorbonne, 1999
No summary/description provided
Nietzsche: science and truth
No summary/description provided
Arqueología: arte, historia, antropología: análisis filosófico de la génesis y desarrollo de una disciplina
No summary/description provided
Freud, a concepção do descentramento e a física moderna
No summary/description provided
Understanding admissibility
No summary/description provided
Truth and historicism in Kuhn’s thesis of methodological incommensurability
No summary/description provided
Are colors real?
No summary/description provided
Introduction: where experience matters
No summary/description provided
Les possibilités de l’expérience: mathématiques, aperception pure et aperception empirique dans la Critique de la raison pure de Kant
No summary/description provided
On the possibility and reality of introspection
No summary/description provided
2025-10-28T12:18:41Z
Bitbol, Michel Petitmengin, Claire
Eleições e ditaduras: um paradoxo estável - comentário
No summary/description provided
La psycho-phénoménologie, théorie de l’explicitation
No summary/description provided
A mathematician’s view on mathematical creation
No summary/description provided
On the source of mathematical intuition
No summary/description provided
Long-term locoregional recurrence in patients treated for breast cancer
Background/purpose: Locoregional control in breast cancer is a fundamental part of treatment and determinant for survival outcomes. It has been reported that most locoregional recurrence (LRR) events occur in the first 5 years after treatment. However, LRR continue to occur after this timeline, with unclear risk factors and unknown survival impact. Methods: Retrospective singe-centered cohort of patients treated for primary breast cancer, between January 2002 and December 2004. Primary outcome was LRR; secondary outcomes were overall survival (OS), disease-free survival (DFS), and predictive factors for LRR. Results: This analysis included 1001 patients, of which 959 (95%) had invasive carcinoma. A mastectomy was performed in 501 (50%) and 500 (50%) had breast conservative surgery (BCS). Median follow-up time was 197 [Inter-quartile range (IQR) 96-211] months. Global LRR rate was 7.6%, with median time to recurrence of 45 [IQR 21-91] months. There was no difference in LRR rate after mastectomy vs BCS, adjusted to tumor stage (p > 0.05). The 10-year OS and DFS rates were 68.4 and 77.8%, respectively. Factors associated with LRR were metastatic axillary lymph nodes and high histologic grade (p < 0.05). Estrogen-negative (ER) tumors had higher LRR rates than ER-positive tumors in the first 5 years (p < 0.05); but no difference was observed with longer follow-up (p > 0.05). LRR was associated with OS (p < 0.05). Discussion and conclusions: Global LRR in this cohort was 7.6% (with over 16 years of follow-up). LRR associates with decreased OS. Time to LRR varies significantly with tumor biology, supporting differentiation of follow-up regimens.
2025-10-28T12:20:21Z
Costeira, Beatriz da Silva, Francisca Brito Fonseca, Filipa Oom, Rodrigo Costa, Cristina Moniz, João Vargas Abecasis, Nuno Santos, Catarina Rodrigues
O futuro da educação
No summary/description provided
Os arquivos no direito internacional
No summary/description provided
2025-10-28T12:20:07Z
Pinto, Eduardo Vera-Cruz, 1961-
Homenagem ao Prof. Doutor José de Oliveira Ascensão
No summary/description provided
2025-10-28T12:09:08Z
Franco, António de Sousa, 1942-2004
A Constituição Fiscal Portuguesa
No summary/description provided
Apreciação da dissertação de doutoramento da Mestra Maria Benedita Malaquias Pires Urbano
No summary/description provided