RCAAP Repository

Learning can occur in a variety of environments and one of them is virtual, including social media sources, blogs and websites. It’s in this perspective, that we present the Networks Project of the Outlab of Intellectual Technologies - LTi, which has the proposal to deepen the studies of the scientific field of Information Science, while considering the importance of learning networks, according to the regime and mediation of information, with the help of the information literacy applied in the Portal of the LTi, while not understanding social action as a way of life. For this reason, we seek to explore what informational skills we can indicate in the Portal of the LTi. We aim to analyze the Portal, within the scope of the information literacy, identifying the elements of the information regime of the Lti; comparing the standards and frameworks of the information literacy of the devices and artifacts and also describing the information literacy of the LTi Portal. For this purpose, we used the methods of documentary research in a virtual environment, based on a qualitative, exploratory and descriptive nature. Data collection was made on the LTi website, organized into categories of information skills, according to the Standards and Information Competency Framework for Higher Education, proposed by the Association of College and Research Libraries. It was concluded that the frameworks can cover more informational skills, providing more benefits to students and users regarding the standards of competence. We recommend an epistemological deepening of the information regime and competency models based on the framework, since this structure is more complete and applicable. Also that the informational skills which are the following: to identify, to access, to search, to evaluate, to organize and to use are promoted by teachers, librarians and all information professionals to their students and users so that they develop increasingly advanced innovative informational services and products.

The exalted population growth rate observed through the years reflects a higher water demand. This natural resource is not found homogeneous in state of nature and it becomes scarce in many regions, so the dispute over its use is one of the consequences. Given the delicate scenario, it is very important to adopt actions that provides the conservation of water in various activities. The industrial sector is responsible for a large part of the consumption of drinking water, maintaining the proportion for the generation and consequently discharge of effluents. The aim of this study was to evaluate the efficiency of the use of the Membrane Bioreactor (MBR) as a technology that provides better efficiency in the treatment of industrial effluents by means of replacing or combining this new technology with the conventional treatment. The effluent was characterized by physical-chemical parameters for this purpose. The LaCom was equipped with a 12L bench-scale bioreactor containing a flat plate of an ultrafiltration membrane, filled with effluents up to 10 L, for the monitoring of the removal efficiency in the biological treatment carried out. The analyzes realized were pH, sedimentable solids, Total Suspended Solids (SST), Chemical Oxygen Demand (COD) and Biological Oxygen Demand (BOD). Through the characterization of the effluent and the permeated, it was possible to calculate the average value for each parameter analyzed and the efficiencies of this treatment for some of the parameters. Total suspended solids presented 92.4%, COD analyzed with Pastel UV revealed 96.5 %, COD conventionally analyzed reached 99% and BOD 92.2%. The results allowed to verify and to prove the efficiency of the treatment of this type of industrial effluent by means of an ultrafiltration membrane. From analyzes and with the intention of applying the reuse in the industry, it was concluded that the permeated came out as expected, achieving a very satisfactory removal efficiency. Moreover, it can be reused in some industrial processes, always taking into account the type of process with the required quality. However, existing legislation and standards superficially addresses the reuse. When in fact it would be a priority to be discussed and applied in industries or other establishment.

Down syndrome is caused by a genetic disorder known as trisomy 21, which generates distinct health problems and consequently very low levels of physical fitness. Physical fitness that is considered an important health marker and a predictor of morbidity and mortality is a fundamental outcome to be analyzed because it seems to facilitate the continuous involvement in physical activities throughout life. The aim of this study was to compare the responses observed in physical fitness indicators (muscle strength, cardiorespiratory fitness, lean mass, fat mass, bone mineral content, flexibility, speed, agility and laterality) of adolescents with Down syndrome exposed to a 6-month multicomponent intervention program and to follow up these responses after 6 months and 1 year of intervention. The sample was composed of 14 adolescents with Down's Syndrome, living in the city of João Pessoa and participating in the "Escolinha + Movimento" project at the Federal University of Paraíba. Physical fitness was assessed by dual-emission Densitometry and physical tests constituting the battery Assessing Levels of Physical Activity (ALPHA) and Koordinations Test für Kinder (KTK). The mean and standard deviation were calculated. Friedman's variance analysis and non-parametric multivariate analysis of variance were used. The magnitude of the effect between the times was calculated using Cohen's d as reference. The analyzes were performed using the Software Statistical Package for Social Sciences - version 24.0 and the software R for nonparametric multivariate analysis of variance. There was a significant improvement in lean body mass (p = 0.003), strength (p = 0.015), velocity (p = 0.028) and agility (p = 0.003) 0.001). For flexibility, the results were marginally significant (p = 0.060). It is noteworthy that even after 1 year without intervention, the participants presented better values when compared with the baseline.

One of the possible forms of interaction in distance education (DE) occurs through printed didactic material (PDM), which acts as a link between student and content, supplying the teacher’s physical absence. Once it has diversified dynamics and characteristics compared to the material for face-to-face teaching and because it is often the only source of study to which the student has access, it is necessary that the PDM for DE be planned, developed and applied respecting the specificities that the modality requires and also with the purpose of facilitating the comprehention of the content by the student. Thus, special attention should be given to the production process, which is organized in stages with different activities and different agents, among them the teacher-author, responsible for the preparation of the text, and the reviewer, in charge of the revision of this text. The interaction between these two subjects is the theme of the present work, once it is carried out, discursively, in the materiality of the text, through the activities of writing, revision and textual rewriting. Thus, the general objective of this research is to investigate how the student is involved in the interaction between the reviewer of texts and teacher-author in the production process of the PDM from the Licentiate Letters Course in Distance Learning at Federal Institute of Education, Science and Technology from Paraíba. For that, 108 excerpts were analyzed (half composed by the original texts of the teacher-author with the interventions of the reviewer and half by the rewritten texts postintervention) that are part of 29 lessons of 11 curricular components, referring to the first two periods of the course, reviewed by three reviewers. This research, inserted in the Applied Linguistics area, has a qualitative-interpretative character and uses documentary corpus. For data analysis, the interventions of the reviewer were classified according to the typology of Serafini (1994) and Ruiz (2001). In addition, the research was based on the theoretical postulates of the Sociodiscursive Interactionism, mainly related to the production conditions of the PDM from Letters Course (BRONCKART, 1999), to the characterization of this material as textual genre (BAKHTIN, 2000; BRONCKART, 1999; VOLOCHINOV, 2014), to the concept of language action and the capacities that are mobilized in it (BRONCKART, 1999, 2006, 2008; CRISTOVÃO, 2007; SCHNEUWLY; DOLZ, 2004). Among the results, it is emphasized that the intervention of the reviewer is not a purely objective activity, because this professional, in and by the language, constitutes him/herself as subject and does not act, simply, in the sphere of the language, once the revision goes beyond the simple hygiene of the text and has a discursive nature. The review is made considering the physical and sociosubjective production context of the text and the textual genre; it focuses the text in its full dimension, encompassing the different language abilities. And the sociodiscursive interaction that occurs between reviewer and teacher-author contributes so that the PDM can fulfill its pedagogical purposes too and, consequently, contemplate the student’s teaching and learning process, once the student is involved in this interaction.

Regions with tropical climate, like the Brazilian northeast, offers different real conditions compared with the STC conditions, for Photovoltaic (PV) systems. Because of that, this study collected different researches and expressions used to calculated the FV operating temperature (Tc), in order to determine which of those expressions better approach to the measured Tc under real operating conditions for a PV system connected to the grid, in a tropical region. During this study, were determined that apart of the ambient temperature, the irradiance and the wind speed, the relative humidity can also affects the PV performance and temperature, because the relative humidity interrupts the solar irradiance rays, and also increases the cell temperature. Out of ten equations found in the literature, the expressions that better approach to the measured cell temperature (Tc) were the proposed by Tamizhmani (±2,11%) and Loveday & Taki (±3,25%). Using the measured database, and considering the relative humidity, it was also proposed a new linear model for Tc, with a MAE (Mean Absolute Error) of ±1,45%, suitable for the m-Si PV models installed on the CEAR building, in a tropical climate.

This work investigated the anaphoric processing of repeated names and full pronouns in Brazilian Portuguese (PB), focusing on theoretical and methodological aspects related to the effect of Repeated Name Penalty (PNR), which consists of an increase in the cost of processing repeated names when compared with pronouns in the establishment of coreferencing in certain syntactic and discursive contexts. This effect was initially found and called the “repeated-name penalty” by Gordon et al. (1993), when conducting a study in English to test the prediction of the Centering Theory (GROSZ et al., 1983, 1995), which assures that the pronoun is the preferred anaphoric form to retake the most prominent antecedent in the discourse. In addition, the PNR was confirmed in other studies conducted in English (GORDON and CHAN, 1995; CHAMBERS and SMYTH 1998; KENISSON and GORDON, 1997) and in other languages such as Chinese Mandarin (YANG et al., 1999) and French (ERNST, 2007). In Brazilian Portuguese, there are differences in the PNR research results, based on the assumptions of Gordon et al. (1993), some attested to the occurrence of this penalty (LEITÃO, 2005; QUEIROZ and LEITÃO, 2008; LEITÃO and SIMÕES, 2011; GONDIM and LEITÃO, 2012; LEITÃO, RIBEIRO and MAIA, 2012; LIMA, 2014; BARBOSA, GONDIM and LIMA, 2016) and others pointed out that this effect does not exist in our linguistic system (MAIA and CUNHA LIMA, 2011, 2012; MAIA, 2013; LIMA, 2015). We observed that among these contrasting studies in PB there are differences in the experimental materials used that involve several factors, both linguistic and methodological. Based on this, we conducted a series of five experiments through the self-monitoring reading technique, manipulating, isolating / controlling and relating some factors, trying to observe if they influenced the occurrence of PNR in order to help clarify the divergences between PB studies. In this multifactorial perspective, in the experiments we manipulate the following factors: Type of Resumption (repeated name, full pronoun); Number of antecedents (one antecedent, two antecedents); Type of sentence (juxtaposed sentences, coordinated sentences), and we controlled the factors: type of final task (task that focused on the antecedent, task that did not focus the antecedent); Form of segmentation / measurement of reading time (stimuli divided into several segments with measurement of reading time only of the anaphoric element, stimuli divided into segments corresponding to sentences with gauging the reading time of the entire sentence that contained the anaphora). The results pointed to a possible interaction between these factors influencing the occurrence or not of PNR, strengthening our general hypothesis that this penalty is a multifactorial effect, which occurs due to the joint action of several factors.

Urbanity can be understood as the balance between the spatial and the social dimensions which form the urban space; e.g. a situation where security has been provided on streets and on sidewalks; public spaces which are suitable for social activities and potentialized by containing a diversity of functions, as well as the presence of people of different social classes, gender and age. This kind of urban quality is becoming scarcerer on contemporary brazilian cities, having mistaken and permissive public interference and the rise of urban violence as some of the key cause factors. Altiplano Cabo Branco neighbourhood, at João Pessoa/PB, is a privileged spot for urbanity investigation, once it contains, in a somewhat restrict observation space two radically opposed and stereotyped displaces for a city, which have been built mainly after the approval of Public Decree 5.844/07, at 2007. This work means to understand the connection between space and society on the three main sectors which compose the Altiplano based on the concept of urbanity. It consists of a study about public spaces, physical space displays, building typology and public-private interface on the neighbourhood; as well as the social effects of those situations, which can be perceived on the way the space is used and on research data collected throw interviews with the local population. This research proposes a physical space approach to its object obtained throw morphologic analyses and the filling of index cards based on the key authors; it also promotes a social approach throw the analyses of the social behavior of the users, interviews with them and in loco examination of the urban space. Throughout this research the influence of public spaces' quality factors, spatial arrangements and public-private interface is made evident. On the other hand the fear for urban violence appears as the main cause for abandoning public spaces by a share of the population. The conclusion is that the use of public spaces occurs at times by overcoming deficiencies which would appear to inhibit all sort of public space use: Friendship between neighbours and the lack of private spaces' quality are some of the factors that influence on this behavior. This research calls attention to the consequences of sudden changes on urban display without proper planning only to satisfy the wishes of a specific and homogeneous group within the population. It concerns also about a factor known as "fear culture", which influences deeply the relation between users and the public space surrounding them, specially by a determined share of the society. Through this complex and contemporary view of the urban space it is made possible to discuss prospects and foresee the influences of such reality of a fragile and deficient urbanity which tends continue to fade.

Soils in the world present problems of water erosion due to the impact of the rain drop on the soil surface, aggravating the superficial crusting and erodibility of the soils. However, agricultural gypsum acts as a reducer of surface crusting, by promoting the flocculation of clays, increasing the stability of aggregates and reducing dispersion. The objective of this study was to evaluate the erodibility of entresulcos and superficial crusting in semi-arid soils under the application of agricultural gypsum. By means of simulated rainfall tests, experiments were carried out to measure the erosion of entresulcos, under open soil conditions with and without the application of agricultural gypsum. The experimental plot has a useful area of 0, 3481m2 and a slope of 0.10 mm-1. The rains were simulated at intervals of 0, 7, 14, 21 days, with mean mean intensity of 85 mm h-1 for 75 minutes. Hydraulic flow variables, disintegration rate, total soil losses, erodibility, suspended sediments, surface roughness, surface crusting, crust microtexture and aggregate stability were evaluated. The soils presented laminar regime and subcritical flow, characterizing the formation of erosion in entressulco. The highest disaggregation rates, soil losses and suspended sediments in TCo and RLe occurred in test 1, due to the direct impact of the rain drop, and intrinsic characteristics of each soil. The erodibility was reduced when agricultural gypsum was applied, due to the flocculating effect of the interaction between the colloids of the RL and greater susceptibility to surface crusting, influencing all other properties in this study. The occurrence of a higher number of simulated rainfall would increase the roughness values, altering the hydraulic variables of the runoff in order to reduce sediment transport.

The objective of this study was to evaluate the effects of energy sources associated with a homeopathic product on the energy and nitrogen balance of confined lactating cows. The experiment was conducted at the Regional Technological Development Pole of Agribusiness in Alta Mogiana, Colina-SP. Sixteen crossbred Holstein x Gir cows were used in the medium third of the lactation with an average weight of 550 kg grouped in homogeneous groups regarding milk yield, lactation period and parity, distributed in a 4x4 Latin square experimental design in factorial arrangement 2x2. The treatments consisted of concentrate with or without inclusion of 50 g / cow / day of the homeopathic product and variation of two energy sources (ground corn and citrus pulp). Ground corn as a source of energy in the diet provided the highest averages (P <0.05) for dry matter intake, weight gain, net lactation energy, intake and nitrogen secretion. There was effect of homeopathic product (P <0.05) on retention and nitrogen balance. The energy sources associated with the homeopathic product were not influenced (P> 0.05) on body weight, body condition score, net energy consumption (EL), EL maintenance, balance and efficiency of EL use. Therefore, the energy source from ground corn in the diets provides better nutrient balance in lactating cows in the middle third of lactation.

Goat milk is a worldwide activity, but a large part of goat milk is produced in small farms and processed in a traditional way, presenting some bottlenecks, such as low daily volume per animal and consequently property, besides the seasonality in production. In this way, the legislation allows for the freezing of goat's milk in producing establishments, provided that it is pasteurized prior to storage. The objective of this study was to evaluate the nutritional composition (fat content, fat in dry extract, protein and total dry extract) and microbiological quality (total and thermotolerant coliforms) of “Coalho” cheese produced with pasteurized goat milk and frozen for different periods. The design was completely randomized and the treatments consisted of the “Coalho” cheese manufactured immediately after the pasteurization and with 51, 90 and 128 days of freezing, totaling four treatments and three replicates. There were no significant changes in relation to total dry extract, fat in dry extract and protein, with respective averages of 47.26; 46.83 and 21.54%, but significant variation (P <0.05) was observed in relation to the fat content, whose values were 23.16; 22.34; 21.78 and 21.18% for days 0, 51, 90 and 128 days of freezing, respectively. For the microbiological analysis, total coliforms > 1.1 x 104 NMP/g were observed and for thermotolerant coliforms, values of 7.83 x 103; 8.6 x 102; 7.85 x 102 and 7.34 x 103 NMP/g for days 0, 51, 90 and 128 days of freezing, respectively. The production of “Coalho” cheese from frozen goat's milk is a viable alternative; however, there is a need for adjustments in the process in order to improve its microbiological quality.

Basal Cell Carcinoma (BCC) is a cutaneous neoplasm that originates from epithelial basal cells that have lost their capacity for normal differentiation and keratinization. It is one of the most frequent types of skin tumors. BCCs are characterized by aberrant regulation of the Sonic Hedgehog pathway, typically through the loss of the PTCH1 receptor and activation of the SMO receptor, resulting in the deregulation of the processes involved in cell growth and proliferation. The change in the Hedgehog cell-signaling pathway has been detected in many human cancers, being deregulated in more than 30% of human cancers, including BCC, medulloblastoma (MB), melanoma, breast, prostate, lung, pancreas, cervical and cervical cancer. SNPs (Single Base Nucleotide Polymorphism) occur frequently in the population, such variations in the genome may be the subject of study as susceptible to disease susceptibility, including cancer. Studies have associated a number of SNPs in promoters associated with gene silencing induced by methylation in various types of cancers. SNPs on the CpG islands located in gene promoter regions are proposed as being associated with multiple diseases. The objective of this study was to perform genotyping of SNPs in the promoter region of the SMO gene in BCC samples and to determine if there is an association of these SNPs of the gene in question with the susceptibility to the development of BCC. One hundred samples of paraffined tissue from patients from the State of Paraíba with histopathological diagnosis of BCC were analyzed for each polymorphism. The results were obtained by DSASP - Dideoxy Single Allele - Specific PCR (Dideoxy Single Allele Specific - PCR). The software Bioestat - version 5.3 and Haploview 4.2 were used for the statistical analysis and application of Chi-square test and Fisher's exact test, considering a level of significance 5%. The analuzes suggest that the SNP rs538312246 is Hardy-Weinberg equilibrium, therefore, it did not present significant association with BCC in the analyzed samples (X2 = 2,343 and P < 0,1258). However, the SNPs rs375350898 and rs75827493 located in the CpG Island region of the SMO gene promoter were significantly associated with BCC in the analyzed samples (X2 = 27,740/21,500 e P < 0,0001), as well as, the SNP rs75827493 showed a significant association with the BCC of the nodular subtype in the analyzed samples (P < 0,0069). Therefore, the results suggest that SNPs rs375350898 and rs75827493 are potential molecular markers for BCC susceptibility.

This study addresses the subject of the death rites in the urban context of the city of Crato, which is located in the metropolitan region of the Cariri in the State of Ceará, Brazil. Our intention is to discuss the countryside experience from the death cerimonial acts that occur in the scenario of a medium-size city. It is focused on discussing the contemporary processes of familiarity with death, which is established by (i) death locations; (ii) the referrals to the funeral homes and burial; (iii) the differences seen before death; (iv) the deceased person in the ritualistic establishment; and (v) the development of the death care industry in the aforementioned urban context. In order to carry this out, the participant observation method was adopted as a data collection method, which enabled the accompanying of the accomplished procedures and rituals. We aimed to understand the various elements that make up such funeral traditions by taking into consideration all of the death-related aspects of the city. The ethnography begins by the following of the memorial services in the funeral homes of the city in question as well as of the burial ritual. We observed a dynamics in the events and its differences, especially in the ritualistic establishments and in the social treatment given to the deceased body. Therefore, we pondered how the funeral traditions are conditioned to: (i) the individual´s status, (ii) the cause of death and (iii) the death market, where the city acts as a manufacturing space of a funeral tradition that acts on existing social class segmentation and differences.

The present dissertation aims to identify and analyze the sale strategies of products in three specific sectors2 of the free fair on the Itapororoca city, Paraíba state. The ethnographic clipping was made from the fruit, vegetable and clothing sectors, more precisely, fruit fair, vegetable fair and clothing fair, respectively. The theoretical approach was based on authors such as Agier (2011), Gonçalves & Abdala (2013), Leite (2001), Magnani (1996, 2002), Machado (2013), Paz (2016), Silva (2015), Sato (2012), Simmel (1983), Vedana (2004, 2008, 2013, 2017) and Velho (2013, 2011). From the Urban Anthropology perspective, this work emphasizes the discussions about the public space appropriations and the sociabilities and strategies in the free fair sale. The qualitative research had the main method the ethnographic description that also used the photographic camera the research tool. The aim was to observe and understand the social practices and activities developed by the marketers by perceiving the selling strategies used to offer merchandise in each of these sectors. The focus of the research was restricted to the observation of social relations between marketers and customers, those who sell and who buy at the fair. The free fair happens weekly on Mondays and attracts a large number of different people from the municipality and from surrounding towns. The public space of the fair enchants all the people who pass through it, because of the variety of goods, colors, smells, sounds and tastes, besides being a stage for diverse social, religious, cultural and political manifestations. In this heterogeneous context of people, goods and cultural manifestations, that the marketers use varied strategies to sell their merchandise, and at the same time strengthen the ties of sociability with the customers.

This thesis is dedicated to the investigation of the universal properties of the electronic transportation in mesoscopic system. At the theoretical level, we introduce the chiral symmetry in chaotic ballistics cavities creating the so-called chaotic billiards of Dirac. For this exact analytical approach, we initially used the diagrammatic method proposed by Brouwer and Beenakker and we built a generalized theory of the integration on the unitary group. The whole calculation incorporates the effect of the chaos through the use of the theory of random matrices. In particular, we calculated physical observables of transportation, such as, the conductance and the power of the shot’s noise. We presented exact results for the observable of transportation relevant in billiards of Dirac chaotic and, posteriorly, compared to the results of Schrödinger billiards, displaying the concerned peculiarities to the universal classes chiral and the classes of Wigner-Dyson. In this context, we presented the study of the crossover of the orthogonal circular ensemble to the unitary circularensembleandthereasonoftheweaklocalizationcorrectiontothenoisepotentialof the shot and to the conductance of the billiard of Dirac.

With technological development and its repercussions in all spheres of modern life, electric energy assumes the role of essential good for life in society, having an influence on both economic and public health issues. Given this essentiality, a special question arises as to its production mode and how it can affect the quality of life of future generations. It is known that non-renewable energy sources have an immense potential for damaging the environment, but only when the results of decades of degradation become palpable does the interest arise in seeking alternative means of production that are committed to sustainable development. In this context of environmental awareness in energy production, not long ago, European and Asian countries pioneered in the production of photovoltaic energy, a type of renewable energy. Although Brazil possesses several characteristics to occupy a relevant place in the production of such type of energy, because it has particularly favorable weather and irradiation conditions, it falls far short of the use of its potential in terms of energy use. Therefore, this study seeks to analyze the barriers that impede the development of photovoltaic energy, especially in the Brazilian state of Paraíba, by using a bibliographic and documentary research based on periodicals, books and databases to compare incentive programs that have influenced the development of photovoltaic energy in countries such as China, Germany and Japan (Feed-inTariff, tax reductions and tax credits). In addition, questionnaires were used to verify, in the opinion of a group of stakeholders, which factors interfere most in the local scenario. The results obtained guarantee the importance of government participation in the growth and development of photovoltaic energy in Brazil. Without efficient regulatory action, whether through political or economic incentives, this will hardly happen or will take much longer to occur than it really should.

The present work analyzed the influence of hydrogen on the quasistatic toughness of welded joint dissimilar, consisting of AISI 8630M and ASTM A-36 steel base metals, with AWS ERNiCrMo-3 filler metal (commercially known as INCONEL 625). This joint, which is one of the most used in the oil industry, has presented brittle fractures in the ZTA regions, as a consequence of the metallurgical transformations and residual stresses caused by the thermal welding. The fracture toughness parameter used was the crack tip aperture displacement, known as Crack Tip Open Displecement (CTOD). Because it was a welded joint, the specimens used were of type SE (B), submitted to three-point bending and tested in the air after previous hydrogenation. The hydrogenation of CTOD specimens was performed in NaCl solution under loads of -650 mVSCE, -850 mVSCE and -1100 mVSCE. The electrochemical permeation tests used in the quantification of the retained hydrogen were performed in both the ZTA and the MB at two load levels of -650 mVSCE and -1100 mVSCE. In terms of the CTOD parameter, the results did not indicate the influence of the hydrogen in the welded joint embrittlement, analyzed in the three levels of established hydrogenation preloads. In turn, in terms of hydrogen permeation, there was an increase in the number of trapping sites of HAZ compared to MB.

Through the union of two approaches of Artificial Intelligence, Knowledge Representation via ontologies, and the treatment of incomplete information through the use of Bayesian Networks (BNs), this work aims to create a methodology for the construction of BNs based on ontologies of the health domain in order to provide clinical decision support. In order to evaluate the methodology, it was applied to an ontology of the Nephrology domain, more specifically of Chronic Kidney Disease (CKD) from which a BN was built. To obtain the probabilities of the Bayesian Network generated, it was used real clinical cases from a database of patients from the Lauro Wanderley University Hospital in the State of Paraíba. For that, it was used techniques such as: direct probability specification, marginal probability and conditional probability. In this way, the conditional probability table was constructed, for the obtained nodes of the BN. Given the results obtained with the experimental evaluation, where the methodology was applied, it was possible to observe the creation of new knowledge based on pre-existing knowledge. The generated network also enabled the extraction of probabilistic knowledge of an ontology by the use of BN, allowing the obtaining of knowledge not provided by the ontology, due to non-existence and/or uncertain information.

According to data from the National Cancer Institute José Alencar Gomes da Silva (INCA), in the biennium 2018-2019, for each year, a value of 600 thousand new cancer cases in Brazil is approaching. As therapeutic output to reach the important population number affected by this disease, there are antitumor antibiotics, antineoplastic agents where doxorubicin is inserted. Despite its effectiveness in fighting tumor cells, its use may cause adverse reactions such as cardiotoxicity. In pharmacological approaches, a substance that has potential in the area of cardiac protection is Angiotensin- (1-7), an endogenous heptapeptide that participates in the renin-angiotensin system. Therefore, the objective of this study was to investigate the effects of Angiotensin- (17) on the prevention and treatment of toxicity caused by Doxorubicin. In this study 35 adult Wistar rats (Rattus novergicus), weighing 160-278g, were used from the Biotério Prof. Thomas George of the Federal University of Paraíba. The animals went through a cycle of six weeks of experimentation, being divided into 6 groups: Control Saline, Control Ang- (1-7), Control doxorubicin, Preventive 1 and 2, and Treatment group. The animals were submitted to 3 echocardiographic evaluations during these weeks and at the end of the treatment were euthanized, with subsequent evaluation of the following organs weight: heart, lung, kidneys (L and R), spleen and liver, besides morphological analysis macroscopic examination of the animals organism (with photographic record execution). In the evaluation of survival, the Control Saline Solution group and Control Ang-(1-7) arrived at the end of the experiment with all live animals, in opposition to the treatment groups that received Ang-(1-7) and doxorubicin. In the Doxo and Treatment control groups there was a decrease in the body mass value of the animals, besides characteristics such as apathy and dehydration and diarrheal feces with mucus. The control group Saline Control in the evaluation of the necropsy presented a morphology with hemorrhagic foci in the lungs, white patches in both kidneys and only one of the rats of this group was able to observe macroscopic morphological normality. The control Ang-(1-7) group presented normal morphological characteristics. The animals in the groups receiving doxorubicin had characteristic stiffness in the organs, especially in the liver, besides the accumulation of fluid in the peritoneal cavity, hemorrhagic foci in the lungs and in one animal there was an increase in the seminal vesicles and gallbladder , it is noteworthy that in the groups in which Ang- (1-7) interaction with doxorubicin also showed an increase in lung volume. Regarding left ventricular function, the animals showed a similar profile between the treatment groups and about the structure there was a decrease in the diastolic diameter, interventricular septum and posterior wall of the left ventricle compared to the Control group. The control group Ang- (1-7) behaved the same as the Control group, showing that Ang- (1-7), when administered alone, does not promote changes in the organs. Isolated heart mass showed a reduction in the groups Control doxorubicin, Preventive 1 and Treatment, but in relation to the body mass, we verified that the proportion was not altered between the groups. The isolated lung mass was altered in the Preventive 1 and Preventive 2 groups and in the organ mass/body mass ratio of the animal, this increase in lung volume can also be observed in the Control doxorubicin and Treatment groups. The spleen of the animals presented alteration only in Preventive 2 group. We did not find any difference in the kidney mass (L and R) between the treatment groups, but we observed that if the organ mass/body mass ratio was observed, there was an increase in the groups that received only doxorubicin at the beginning of the experiment. Finally, the liver mass of the animals did not show any difference between the groups when observed alone, but when considered the body mass of the animal, the groups Control doxorubicin, Preventive 1 and Treatment showed an important difference of the Control Saline group. In view of the results it was not possible to analyze the prevention of cardiotoxicity by Ang- (1-7), and when administered in combination with doxorubicin the effects were too deleterious.

This thesis defends that subjects coming from a Potiguara cultural identity re-signifies their knowledge, built along their lifetime trajectory, through the knowledge and experiences leamed in the formative processes from their entrance into the university. Thus, to reflect about the experiences that involve this thesis, the theoretical references were constituted in the interrelation between several fields of knowledge and practice, such as university (Saviani 2007; Boaventura 2013); ethnicity and native identity (Hall 2006; Ianni 2004); multiculturalism, interculturalism and cultural studies (Candau 2008; Jovchelovitch 2011; Grando and Hasse 2001; Silva 2000; Brandão 2002). It includes Philosophy, Anthropology, Sociology and Education, highlighting the concept of identity as central category (Hall 2009; Bauman 2005; Silva 2013; Elias 1994; among others). Therefore, the general objective of this qualitative research was to investigate, from the life narratives of the native youths, the ways in which they re-signify their identity considering the academic experiences lived in the Executive Secretariat course, offered at campus IV of UFPB, in the Mamanguape Valley region. The specific objectives are: identify how the native students are inserting themselves into the academic universe; recognize fundamental subjects, spaces and processes so that these young people can build intersections between their cultural identities and the academic knowledge through an intercultural dialogue; perceive, from their lifetime trajectories, how their experiences could contribute to the entrance in the university and the choosing of a higher education programme. The methodological approach adopted was the (auto) biographical research because it allows the articulation of meanings from the centrality of narratives of the young Potiguara Natives, considering the concepts of experience (Larrosa 2002; Delory-Momberger 2006), training experience (Josso 2004) and narratives (Ricouer 1994; Benjamin 1994; Bertaux 2010). The procedure for the production of the narratives was a dialogical group (DG) with the participation of three native students, comprising the following activities: questionnaire application on personal, academic and professional information; practical activities for the development of the concepts underlying this thesis; and, lastly, the realization of the narrative. The participant observation, a roaming diary and the analysis of the academic reports of those involved complemented the data collection. We use the discursive textual analysis for the research corpus, under the bias of what Roque Moraes (2014) calls "a storm of light", because this methodology seeks to interpret the productions made and constructed in the qualitative research, representing a hermeneutic and heuristic understanding. Starting from the narratives, we understand moments and processes that made the subjects get involved in activities promoted by the university, seeking their insertion in that space. We also identified the subjects that allowed the intersection between their cultural identity and the academic knowledge, highlighting parents, relatives, friends and professors; and, lastly, we recognized some contradictions and complementarities existing in the intersection between academic and native knowledge, making possible a process ofre-signification of one's own identity.

Outsourcing in Brazil is a practice that dates back to the 1950s, with the coming of multinational automobile industries, extending to other areas and gaining repercussion in the 1970s with the restructuring of production. Because it is a conjunctural issue, it has become a constant theme in the discourses of organizations, workers and government, and can be characterized as a current instrument of precarious work, which already carries in its history a process of exploitation of the worker. ln this sense, the present work aims to analyze the use of the outsourcjng tool in the Federal Institute of Education, Science and Technology of Paraíba (IFPB), specifically regarding the services provided in the conservation and cleaning sector at its Rectory, observing the advantages and disadvantages for the institution and for contract workers. Specific objectives include: analyzing the implementation process of the outsourcing strategy in the public service; investigate the use of outsourcing under the IFPB; and identify the profile of the outsourced professionals who work in the conservation and cleaning sector in the Rectory. Through bibliographic and documentary research a brief history of outsourcing in Brazil was presented, the main concepts that <leal with this theme, its application and legal basis. ln this sense, it appears as a present practice in the private sector as well as in the public service, although in the latter there are particular issues for discussions regarding legislation, which has specific articles for the public segment. The qualitative research was chosen in this work, having as instruments of data collection questionnaires with closed and open questions, made with managers and outsourced workers of the institution. With the analysis of content, it was verified that outsourcing affects the professional practice of workers hired in this modality, so that it impacts in different ways the provision of services, guarantee of their rights, effectiveness and accountability of Public Administration.